SCHEMBL9317458

SCHEMBL9317458

C=CC(=O)OCCCCCCN(C)c1ccc(C=Cc2ccc(S(=O)(=O)c3ccccc3)cc2)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.39
CYP3A4 P08684 1/20 0.39
TSHR P16473 1/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
THRB P10828 1/20 0.38
CTDSP1 Q9GZU7 1/20 0.37
HDAC1 Q13547 1/20 0.36
HDAC8 Q9BY41 1/20 0.36
BCHE P06276 3/20 0.36
ACHE P22303 3/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
LMNA P02545 1/20 0.36
MAOB P27338 4/20 0.35
GAA P10253 1/20 0.35
MAPT P10636 1/20 0.35
AKR1B10 O60218 1/20 0.35
AKR1B1 P15121 1/20 0.35
MAOA P21397 2/20 0.35
KDM4E B2RXH2 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9317451 1.00 ALDH1A1 (0.39) ALDH1A1CYP3A4TSHRMEN1KMT2A
SCHEMBL9317356 0.92 ALDH1A1 (0.44) ALDH1A1MEN1KMT2ATHRBCTDSP1
SCHEMBL9317354 0.92 ALDH1A1 (0.44) ALDH1A1MEN1KMT2ATHRBCTDSP1
SCHEMBL9317088 0.89 MMP14 (0.41) ALDH1A1CYP3A4TSHRMEN1KMT2A
SCHEMBL9317085 0.89 MMP14 (0.41) ALDH1A1CYP3A4TSHRMEN1KMT2A
SCHEMBL9317854 0.89 TSHR (0.41) ALDH1A1CYP3A4TSHRMEN1KMT2A
SCHEMBL9317849 0.89 TSHR (0.41) ALDH1A1CYP3A4TSHRMEN1KMT2A
SCHEMBL9317175 0.87 POLB (0.40) ALDH1A1TSHRMEN1KMT2ACTDSP1
SCHEMBL9317170 0.87 POLB (0.40) ALDH1A1TSHRMEN1KMT2ACTDSP1
SCHEMBL9317404 0.83 THRB (0.54) ALDH1A1CYP3A4TSHRTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5322986-A Methods for preparing polymer stripe waveguides and polymer stripe waveguides prepared thereby EASTMAN KODAK COMPANY (US) 1994-06-21 US disclosed
US-5157541-A Support with dielectric, reflection metal, polymeric electrooptical layers, couterelectrode EASTMAN KODAK COMPANY (US) 1992-10-20 US disclosed
US-5075796-A OPTICAL ARTICLE FOR MULTICOLOR IMAGING EASTMAN KODAK COMPANY (US) 1991-12-24 US disclosed
EP-0422725-A2 High x(2) optical article EASTMAN KODAK COMPANY (US) 1991-04-17 EP disclosed
EP-0422723-A2 Optical article for reflection modulation EASTMAN KODAK COMPANY (US) 1991-04-17 EP disclosed
US-4948225-A REFLECTIVE METAL LAYER, DIELECTRICS, PROTECTIVE COATING EASTMAN KODAK COMPANY (US) 1990-08-14 US disclosed