Known targets — ChEMBL curated mechanism
rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Stearic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT2 | O75908 | 1/20 | 0.52 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.50 |
| ▸ | CES2 | O00748 | 2/20 | 0.50 |
| ▸ | CES1 | P23141 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | ICMT | O60725 | 1/20 | 0.49 |
| ▸ | ALB | P02768 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 6/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Behenic Acid SCHEMBL9316968 | 1.00 | SOAT2 (0.52) | SOAT2SOAT1ALDH1A1EPHX1CES2 | |
| Stearic Acid SCHEMBL9317212 | 0.97 | SOAT2 (0.52) | SOAT2SOAT1ALDH1A1EPHX1CES2 | |
| Glutarate SCHEMBL9316643 | 0.88 | NPC1 (0.53) | ALDH1A1EPHX1HTTNPC1HPGD | |
| Behenic Acid SCHEMBL9316970 | 0.86 | CES2 (0.51) | SOAT2SOAT1ALDH1A1EPHX1CES2 | |
| Stearic Acid SCHEMBL9317247 | 0.86 | CES2 (0.51) | SOAT2SOAT1ALDH1A1EPHX1CES2 | |
| Stearic Acid SCHEMBL9317214 | 0.86 | CES2 (0.51) | SOAT2SOAT1ALDH1A1EPHX1CES2 | |
| Stearic Acid SCHEMBL9469601 | 0.84 | ALDH1A1 (0.56) | SOAT2SOAT1ALDH1A1EPHX1HTT | |
| Diphenylamine SCHEMBL21145265 | 0.82 | GPR84 (0.61) | SOAT2SOAT1ALDH1A1CES2CES1 | |
| Dodecanoate SCHEMBL21145309 | 0.82 | GPR84 (0.61) | SOAT2SOAT1ALDH1A1CES2CES1 | |
| Palmitic Acid SCHEMBL9330998 | 0.82 | GPR84 (0.61) | SOAT2SOAT1ALDH1A1CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5354514-A | Heating mixture of thioamide compound and copper- or lead-containing compound | JUJO PAPER CO., LTD. (JP) | 1994-10-11 | — | — | US | disclosed |