Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.49 |
| ▸ | CTSK | P43235 | 4/20 | 0.49 |
| ▸ | CTSS | P25774 | 3/20 | 0.49 |
| ▸ | ITGAV | P06756 | 2/20 | 0.48 |
| ▸ | ITGB6 | P18564 | 2/20 | 0.48 |
| ▸ | PPARA | Q07869 | 5/20 | 0.47 |
| ▸ | PPARG | P37231 | 4/20 | 0.47 |
| ▸ | ACE | P12821 | 1/20 | 0.47 |
| ▸ | PPARD | Q03181 | 2/20 | 0.46 |
| ▸ | CTSB | P07858 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2300113 | 0.89 | ACE (0.53) | PTPN1CTSKCTSSPPARAPPARG | |
| SCHEMBL14265380 | 0.89 | ACE (0.53) | PTPN1CTSKCTSSPPARAPPARG | |
| SCHEMBL7252358 | 0.81 | PPARA (0.55) | PTPN1CTSKCTSSPPARAPPARG | |
| SCHEMBL8298606 | 0.80 | CTSK (0.62) | PTPN1CTSKCTSSPPARAPPARG | |
| SCHEMBL7475581 | 0.80 | CTSK (0.62) | PTPN1CTSKCTSSPPARAPPARG | |
| SCHEMBL181775 | 0.80 | CTSK (0.71) | CTSKCTSSPPARAPPARGACE | |
| SCHEMBL181807 | 0.80 | CTSK (0.71) | CTSKCTSSPPARAPPARGACE | |
| SCHEMBL181808 | 0.80 | CTSK (0.71) | CTSKCTSSPPARAPPARGACE | |
| SCHEMBL9320047 | 0.80 | CYP1A2 (0.44) | PTPN1CTSKCTSSITGAVITGB6 | |
| SCHEMBL19407482 | 0.79 | GABRB1 (0.45) | CTSKCTSSCTSBALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5346898-A | FOR TREATING FUNGAL INFECTIONS IN MAMMALS | SCHERING CORPORATION (US) | 1994-09-13 | — | — | US | disclosed |