Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 14/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 12/20 | 0.45 |
| ▸ | PPARA | Q07869 | 10/20 | 0.45 |
| ▸ | PTGES | O14684 | 10/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CYSLTR2 | Q9NS75 | 3/20 | 0.41 |
| ▸ | CYSLTR1 | Q9Y271 | 3/20 | 0.41 |
| ▸ | THRA | P10827 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9318883 | 0.77 | PPARG (0.52) | PPARGALOX5PPARAPTGESCYSLTR2 | |
| SCHEMBL7795191 | 0.69 | ALDH1A1 (0.66) | TSHR | |
| SCHEMBL9319067 | 0.69 | PPARG (0.43) | PPARGALOX5PPARAPTGESCYSLTR2 | |
| SCHEMBL8159673 | 0.68 | TSHR (0.47) | PPARGPPARATSHR | |
| SCHEMBL8164075 | 0.68 | TSHR (0.59) | PPARATSHRCYSLTR2CYSLTR1THRA | |
| SCHEMBL2859507 | 0.65 | GPR84 (0.57) | PPARGPPARATSHRTHRATHRB | |
| SCHEMBL14155758 | 0.65 | ALOX5 (0.57) | PPARGALOX5PPARAPTGES | |
| SCHEMBL28064406 | 0.65 | FFAR4 (0.50) | PPARGPPARATSHRCYSLTR2CYSLTR1 | |
| SCHEMBL9099026 | 0.64 | PPARG (0.64) | PPARGALOX5PPARAPTGES | |
| SCHEMBL9099036 | 0.64 | PPARG (0.64) | PPARGALOX5PPARAPTGES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0576603-A1 | PHARMACEUTICAL COMBINATION FOR THE TREATMENT OF PROSTATIC HYPERPLASIA, CONTAINING A 5 ALPHA-REDUCTASE INHIBITOR AND AN ANTIANDROGEN | MERCK & CO. INC. (US) | 1994-01-05 | — | — | EP | disclosed |