Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 2/20 | 0.65 |
| ▸ | PKM | P14618 | 2/20 | 0.60 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | MMP2 | P08253 | 12/20 | 0.56 |
| ▸ | MMP12 | P39900 | 12/20 | 0.56 |
| ▸ | MMP8 | P22894 | 11/20 | 0.56 |
| ▸ | MMP13 | P45452 | 11/20 | 0.56 |
| ▸ | MMP14 | P50281 | 11/20 | 0.56 |
| ▸ | MMP16 | P51512 | 11/20 | 0.56 |
| ▸ | MMP9 | P14780 | 11/20 | 0.56 |
| ▸ | MMP3 | P08254 | 8/20 | 0.52 |
| ▸ | MMP1 | P03956 | 5/20 | 0.52 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.52 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8933453 | 0.81 | PKM (0.62) | HTR6PKMGAAMMP2MMP12 | |
| SCHEMBL931939 | 0.81 | HTR6 (0.77) | HTR6PKMGAAMMP2MMP12 | |
| SCHEMBL14486272 | 0.80 | PKM (0.67) | HTR6PKMGAAMMP2MMP12 | |
| SCHEMBL2004711 | 0.80 | HTR6 (0.71) | HTR6GAA | |
| SCHEMBL28702767 | 0.80 | HTR6 (0.56) | HTR6PKMGAAMMP2MMP12 | |
| SCHEMBL34558 | 0.80 | HTR6 (0.77) | HTR6PKMGAA | |
| SCHEMBL10592283 | 0.79 | GAA (0.61) | HTR6PKMGAAMMP2MMP12 | |
| SCHEMBL30751995 | 0.79 | HTR6 (1.00) | HTR6PKMGAA | |
| SCHEMBL395274 | 0.79 | HTR6 (1.00) | HTR6PKMGAA | |
| SCHEMBL7274484 | 0.78 | MMP2 (0.71) | HTR6PKMGAAMMP2MMP12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0109624-A2 | Process for producing shaped articles made from polyurethane-polyurea which may be cellular | BASF Aktiengesellschaft (DE) | 1984-05-30 | — | — | EP | disclosed |
| US-4313872-A | MONDAZO AND DISAZO DYES | CASSELLA AKTIENGESELLSCHAFT (DE) | 1982-02-02 | — | — | US | disclosed |
| US-4118384-A | DIAZOTIZATION | BAYER AKTIENGESELLSCHAFT (DE) | 1978-10-03 | — | — | US | disclosed |