Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.62 |
| ▸ | MMP2 | P08253 | 11/20 | 0.57 |
| ▸ | MMP12 | P39900 | 11/20 | 0.57 |
| ▸ | MMP8 | P22894 | 10/20 | 0.57 |
| ▸ | MMP13 | P45452 | 10/20 | 0.57 |
| ▸ | MMP14 | P50281 | 10/20 | 0.57 |
| ▸ | MMP16 | P51512 | 10/20 | 0.57 |
| ▸ | MMP9 | P14780 | 10/20 | 0.57 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.56 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.55 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.54 |
| ▸ | MMP3 | P08254 | 7/20 | 0.54 |
| ▸ | MMP1 | P03956 | 5/20 | 0.54 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.53 |
| ▸ | HTR6 | P50406 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Anisole SCHEMBL11531120 | 0.85 | CA4 (0.54) | PKMMMP2MMP12MMP8MMP13 | |
| SCHEMBL931939 | 0.82 | HTR6 (0.77) | PKMMMP2MMP12MMP8MMP13 | |
| SCHEMBL8145743 | 0.82 | PKM (0.62) | PKMRAPGEF4FFAR4GAAHTR6 | |
| SCHEMBL29039869 | 0.81 | FFAR4 (0.52) | KEAP1FFAR4HTR6ALDH1A1 | |
| SCHEMBL12336792 | 0.81 | HTR6 (0.58) | GAAHSD11B1HTR6KMT2AALDH1A1 | |
| SCHEMBL30893040 | 0.81 | GAA (0.60) | RAPGEF4GAAHSD11B1MEN1KMT2A | |
| SCHEMBL8964467 | 0.81 | GAA (0.60) | RAPGEF4GAAHSD11B1MEN1KMT2A | |
| SCHEMBL10592283 | 0.81 | GAA (0.61) | PKMMMP2MMP12MMP8MMP13 | |
| SCHEMBL11114971 | 0.81 | HTR6 (0.65) | PKMMMP2MMP12MMP8MMP13 | |
| SCHEMBL1713160 | 0.81 | HTR6 (0.57) | GAAHSD11B1HTR6MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996024601-A1 | COMPLEXES, PROCESSES FOR THEIR PREPARATION AND THEIR USE | UNIVERSITY COLLEGE DUBLIN (IE) | 1996-08-15 | — | — | WO | claimed |
| WO-1996024601-A1 | COMPLEXES, PROCESSES FOR THEIR PREPARATION AND THEIR USE | UNIVERSITY COLLEGE DUBLIN (IE) | 1996-08-15 | — | — | WO | disclosed |