Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | PTPRC | P08575 | 1/20 | 0.50 |
| ▸ | CLK1 | P49759 | 1/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.44 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.44 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.41 |
| ▸ | FASN | P49327 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9320769 | 0.89 | PTPRC (0.62) | ATMTDP1L3MBTL1PTPRCPBRM1 | |
| SCHEMBL7522889 | 0.76 | PTPRC (0.43) | ATMTDP1L3MBTL1PTPRCALDH1A1 | |
| SCHEMBL9123084 | 0.75 | TSHR (0.52) | L3MBTL1ALDH1A1POLBSRD5A2CA1 | |
| SCHEMBL9320133 | 0.75 | MAPT (0.48) | L3MBTL1ALDH1A1NPC1LMNARAB9A | |
| SCHEMBL8377993 | 0.75 | TDP1 (0.65) | ATMTDP1L3MBTL1PBRM1ALDH1A1 | |
| SCHEMBL9324919 | 0.74 | ATM (1.00) | ATMTDP1L3MBTL1PBRM1ALDH1A1 | |
| SCHEMBL135162 | 0.74 | ATM (1.00) | ATMTDP1L3MBTL1PBRM1ALDH1A1 | |
| SCHEMBL6231834 | 0.73 | ALDH1A1 (0.39) | PTPRCALDH1A1CA1CA2 | |
| Hydrochloric Acid SCHEMBL9365820 | 0.73 | TSHR (0.50) | L3MBTL1ALDH1A1POLBSRD5A2CA1 | |
| SCHEMBL698836 | 0.73 | LMNA (0.71) | ATMTDP1L3MBTL1CLK1DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0515170-A2 | Biscyclobutarene/polymaleimide copolymers | THE DOW CHEMICAL COMPANY (US) | 1992-11-25 | — | — | EP | claimed |
| JP-5178941-A | — | — | None | — | — | JP | disclosed |
| JP-H05178941-A | BISCYCLOBUTARENE/POLYMALEIMIDE COPOLYMER | DOW CHEM CO:THE | 1993-07-20 | — | — | JP | disclosed |
| EP-0515170-A2 | Biscyclobutarene/polymaleimide copolymers | THE DOW CHEMICAL COMPANY (US) | 1992-11-25 | — | — | EP | disclosed |