Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.30 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.30 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.30 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9320720 | 0.89 | MMP1 (0.35) | MMP1MMP2MMP9CYP2D6SLC6A4 | |
| SCHEMBL15869202 | 0.74 | ADORA3 (0.43) | BACE1SLC6A4ADORA3PSMB1PSMB5 | |
| SCHEMBL15869191 | 0.73 | ADORA3 (0.45) | BACE1SLC6A4ADORA3PSMB1PSMB5 | |
| SCHEMBL9320648 | 0.72 | PSMB1 (0.46) | MMP1MMP2MMP9BACE1ADORA3 | |
| SCHEMBL28567449 | 0.72 | MEN1 (0.40) | — | |
| SCHEMBL14066240 | 0.71 | MAPT (0.36) | MMP1MMP2MMP9SLC6A4 | |
| SCHEMBL8755128 | 0.71 | ALDH1A1 (0.36) | CYP2D6SLC6A4PSMB1PSMB5PSMB2 | |
| SCHEMBL11696945 | 0.71 | MEN1 (0.41) | — | |
| SCHEMBL826438 | 0.68 | PSMB1 (0.50) | MMP1MMP2MMP9CYP2D6ADORA3 | |
| SCHEMBL472145 | 0.67 | PSMB1 (0.53) | MMP1MMP2MMP9CYP2D6ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0464408-B1 | Process for preparing star compounds | SEKISUI CHEMICAL CO LTD (JP) | 1994-01-12 | — | — | EP | disclosed |
| US-5102966-A | Addition polymerization of unsaturated ethers using an unsaturated alkenyl polyether adduct as initiator and a cation-donating compound | SEKISUI CHEMICAL CO., LTD. (JP) | 1992-04-07 | — | — | US | disclosed |
| EP-0464408-A1 | Process for preparing star compounds | SEKISUI CHEMICAL CO., LTD. (JP) | 1992-01-08 | — | — | EP | disclosed |