Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9322632 | 0.79 | ZDHHC20 (0.42) | RAB9ANPC1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL19146541 | 0.79 | RAB9A (0.56) | RAB9ANPC1KMT2ASMN1; SMN2ATM | |
| Hydrochloric Acid SCHEMBL9549323 | 0.78 | FAAH (0.42) | RAB9AKMT2AALDH1A1TSHRMEN1 | |
| Hydrochloric Acid SCHEMBL9549305 | 0.78 | FAAH (0.42) | RAB9AKMT2AALDH1A1TSHRMEN1 | |
| Hydrochloric Acid SCHEMBL9549110 | 0.78 | FAAH (0.42) | RAB9AKMT2AALDH1A1TSHRMEN1 | |
| Hydrochloric Acid SCHEMBL9549206 | 0.78 | FAAH (0.42) | RAB9AKMT2AALDH1A1TSHRMEN1 | |
| Hydrochloric Acid SCHEMBL9067351 | 0.78 | FAAH (0.42) | RAB9AKMT2AALDH1A1TSHRMEN1 | |
| Hydrochloric Acid SCHEMBL9549510 | 0.78 | FAAH (0.42) | RAB9AKMT2AALDH1A1TSHRMEN1 | |
| SCHEMBL19145900 | 0.78 | KMT2A (0.64) | RAB9ANPC1KMT2ASMN1; SMN2ATM | |
| Hydrochloric Acid SCHEMBL444004 | 0.77 | RAB9A (0.35) | RAB9ANPC1KMT2AATMMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0423129-A4 | HETEROCYCLIC CONTAINING CELLULOSIC GRAFT POLYMERS | — | 1991-07-31 | — | — | EP | claimed |
| EP-0423129-A1 | HETEROCYCLIC CONTAINING CELLULOSIC GRAFT POLYMERS | GAF CHEMICALS CORPORATION (US) | 1991-04-24 | — | — | EP | claimed |
| WO-1989009239-A1 | HETEROCYCLIC CONTAINING CELLULOSIC GRAFT POLYMERS | GAF CHEMICALS CORPORATION (US) | 1989-10-05 | — | — | WO | claimed |
| US-4831097-A | SKIN AND HAIR TREATMENT; ANTISTATIC AGENT | GAF CORPORATION (US) | 1989-05-16 | — | — | US | claimed |
| EP-0430963-B1 | HYDROLYSIS RESISTANT VINYL LACTAM AMINO ACRYLAMIDE POLYMERS | ISP INVESTMENTS INC (US) | 1994-01-12 | — | — | EP | disclosed |
| EP-0430963-A4 | HYDROLYSIS RESISTANT VINYL LACTAM AMINO ACRYLAMIDE POLYMERS | — | 1991-11-21 | — | — | EP | disclosed |
| EP-0430963-A1 | HYDROLYSIS RESISTANT VINYL LACTAM AMINO ACRYLAMIDE POLYMERS. | GAF CHEMICALS CORP (US) | 1991-06-12 | — | — | EP | disclosed |
| US-4923694-A | HAIR CONDITIONERS; (3-METHACRYLAMIDOPROPYL) TRIMETHYL AMMONIUM CHLORIDE-VINYLPYRROLIDONE COPOLYMER | GAF CHEMICALS CORPORATION (US) | 1990-05-08 | — | — | US | disclosed |
| WO-1990001920-A1 | HYDROLYSIS RESISTANT VINYL LACTAM AMINO ACRYLAMIDE POLYMERS | GAF CHEMICALS CORPORATION (US) | 1990-03-08 | — | — | WO | disclosed |
| US-4831097-A | SKIN AND HAIR TREATMENT; ANTISTATIC AGENT | GAF CORPORATION (US) | 1989-05-16 | — | — | US | disclosed |