Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 20/20 | 0.67 |
| ▸ | CTSD | P07339 | 1/20 | 0.49 |
| ▸ | CTSE | P14091 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8955332 | 0.99 | REN (0.66) | RENCTSDCTSE | |
| SCHEMBL8955003 | 0.92 | REN (0.66) | RENCTSDCTSE | |
| SCHEMBL7335450 | 0.81 | REN (0.58) | RENCTSDCTSE | |
| SCHEMBL9458635 | 0.80 | REN (1.00) | RENCTSDCTSE | |
| SCHEMBL9556735 | 0.75 | REN (0.50) | RENCTSDCTSE | |
| SCHEMBL7331287 | 0.75 | REN (0.63) | RENCTSDCTSE | |
| SCHEMBL7340387 | 0.73 | REN (0.53) | RENCTSDCTSE | |
| SCHEMBL7329310 | 0.73 | REN (0.48) | RENCTSDCTSE | |
| SCHEMBL7385524 | 0.72 | MEN1 (0.61) | RENCTSDCTSE | |
| SCHEMBL7317104 | 0.72 | MEN1 (0.61) | RENCTSDCTSE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0581899-A1 | IMPROVED PROCESS FOR THE PREPARATION OF 1S-(1R*, 2S*, 3R*)]-N-(4-(MORPHOLINYLSULFONYL)-L-PHENYLALANYL-3-(2-AMINO-4-THIAZOLYL)-N- (1-CYCLOHEXYLMETHYL)-2,3-DIHYDROXY-5-METHYLHEXYL]-L-ALANINAMIDE | WARNER-LAMBERT COMPANY (US) | 1994-02-09 | — | — | EP | disclosed |
| WO-1992018486-A1 | IMPROVED PROCESS FOR THE PREPARATION OF [1S-(1R*, 2S*, 3R*)]-N-(4-(MORPHOLINYLSULFONYL)-L-PHENYLALANYL-3-(2-AMINO-4-THIAZOLYL)-N-[(1-CYCLOHEXYLMETHYL)-2,3-DIHYDROXY-5-METHYLHEXYL]-L-ALANINAMIDE | WARNER-LAMBERT COMPANY (US) | 1992-10-29 | — | — | WO | disclosed |