Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 20/20 | 0.50 |
| ▸ | CTSD | P07339 | 1/20 | 0.42 |
| ▸ | CTSE | P14091 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7335450 | 0.77 | REN (0.58) | RENCTSDCTSE | |
| SCHEMBL8955003 | 0.76 | REN (0.66) | RENCTSDCTSE | |
| SCHEMBL9322207 | 0.75 | REN (0.67) | RENCTSDCTSE | |
| Hydrochloric Acid SCHEMBL8955332 | 0.74 | REN (0.66) | RENCTSDCTSE | |
| SCHEMBL7331364 | 0.74 | REN (0.48) | RENCTSDCTSE | |
| SCHEMBL7317104 | 0.73 | MEN1 (0.61) | RENCTSDCTSE | |
| SCHEMBL7385524 | 0.73 | MEN1 (0.61) | RENCTSDCTSE | |
| SCHEMBL7338635 | 0.72 | REN (0.42) | RENCTSDCTSE | |
| SCHEMBL7339328 | 0.72 | REN (0.43) | RENCTSDCTSE | |
| SCHEMBL7336480 | 0.72 | REN (0.38) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5258362-A | Enzyme inhibitors, amides with oxetane ring | ABBOTT LABORATORIES (US) | 1993-11-02 | — | — | US | disclosed |