Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 1/20 | 0.41 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.41 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.41 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | FPR3 | P25089 | 1/20 | 0.35 |
| ▸ | FPR2 | P25090 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9321519 | 0.90 | SHMT2 (0.41) | HRH3SHMT2 | |
| SCHEMBL9322707 | 0.85 | FPR3 (0.40) | CARM1PRMT6PRMT8L3MBTL1HRH3 | |
| SCHEMBL9321377 | 0.84 | HRH3 (0.42) | CARM1PRMT6PRMT8SIGMAR1L3MBTL1 | |
| SCHEMBL9322327 | 0.84 | HRH3 (0.42) | CARM1PRMT6PRMT8SIGMAR1L3MBTL1 | |
| SCHEMBL9321403 | 0.84 | HRH3 (0.42) | CARM1PRMT6PRMT8SIGMAR1L3MBTL1 | |
| SCHEMBL9323677 | 0.81 | SMN1; SMN2 (0.39) | L3MBTL1HRH3FPR3FPR2TSHR | |
| SCHEMBL9323550 | 0.81 | TP53 (0.39) | SIGMAR1FPR3FPR2TP53SMN1; SMN2 | |
| SCHEMBL18289222 | 0.80 | CARM1 (0.53) | CARM1PRMT6PRMT1PRMT8SIGMAR1 | |
| SCHEMBL9324718 | 0.79 | HRH3 (0.45) | CARM1PRMT6PRMT8SIGMAR1HRH3 | |
| SCHEMBL9322157 | 0.79 | HRH3 (0.45) | CARM1PRMT6PRMT8SIGMAR1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5310902-A | Glutamate blockers | NIPPON CHEMIPHAR CO., LTD. (JP) | 1994-05-10 | — | — | US | disclosed |