Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | PNMT | P11086 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CRHBP | P24387 | 1/20 | 0.31 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9775425 | 0.76 | TSHR (0.41) | LMNATSHRPNMTTP53HPGD | |
| SCHEMBL2565196 | 0.72 | TSHR (0.47) | LMNATSHRPNMTTP53HPGD | |
| SCHEMBL31193363 | 0.72 | TSHR (0.47) | LMNATSHRPNMTTP53HPGD | |
| SCHEMBL1798315 | 0.70 | TSHR (0.45) | LMNATSHRPNMTTP53HPGD | |
| SCHEMBL5375946 | 0.70 | TSHR (0.45) | LMNATSHRPNMTTP53HPGD | |
| SCHEMBL20535921 | 0.69 | LMNA (0.35) | LMNATSHRPNMTTP53HPGD | |
| SCHEMBL6049738 | 0.69 | MAPT (0.38) | TSHRTP53HPGDKDM4ECES2 | |
| SCHEMBL29001313 | 0.68 | LMNA (0.33) | LMNATSHRPNMTTP53HPGD | |
| SCHEMBL10398399 | 0.67 | LMNA (0.36) | LMNATSHRPNMTCASP1KDM4E | |
| SCHEMBL241382 | 0.67 | LMNA (0.36) | LMNATSHRPNMTCASP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104893290-B | Radiation-curable silicone composition | 信越化学工业株式会社 | 2020-01-21 | — | — | CN | disclosed |
| EP-0404029-B1 | Substantially odor free, UV curable organopolysiloxane release coating compositions and coating method | GEN ELECTRIC (US) | 1994-02-16 | — | — | EP | disclosed |
| US-4994299-A | Epoxyhaloarylaklsiloxane with polyaryloniumhexafluorometalloid salt photoinitiator | GENERAL ELECTRIC COMPANY (US) | 1991-02-19 | — | — | US | disclosed |
| EP-0404029-A1 | Substantially odor free, UV curable organopolysiloxane release coating compositions and coating method | GENERAL ELECTRIC COMPANY (US) | 1990-12-27 | — | — | EP | disclosed |