SCHEMBL9323709

SCHEMBL9323709

CCO[Si](CCCOC(=O)CC(=O)O)(OCC)OCC

nearest known ligand 0.38

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.38
MGAM O43451 1/20 0.38
SI P14410 1/20 0.38
MGAM2 Q2M2H8 1/20 0.38
FAAH O00519 2/20 0.37
NAAA Q02083 1/20 0.35
POLB P06746 1/20 0.33
EGLN1 Q9GZT9 1/20 0.33
ACHE P22303 6/20 0.33
ALDH1A1 P00352 1/20 0.32
LMNA P02545 1/20 0.32
MAPT P10636 1/20 0.32
HPGD P15428 1/20 0.32
TSHR P16473 1/20 0.32
HSD17B10 Q99714 1/20 0.32
DGKA P23743 1/20 0.32
RAD52 P43351 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9323713 0.91 GAA (0.46) GAAMGAMSIMGAM2FAAH
SCHEMBL15806575 0.88 GAA (0.54) GAAMGAMSIMGAM2FAAH
SCHEMBL1070484 0.86 GAA (0.38) GAAMGAMSIMGAM2FAAH
SCHEMBL176416 0.85 HTR2C (0.38) NAAAEGLN1ALDH1A1LMNAMAPT
SCHEMBL176417 0.84 DGKA (0.42) GAANAAAALDH1A1MAPTDGKA
SCHEMBL1224968 0.84 NAAA (0.52) GAAMGAMSIMGAM2FAAH
SCHEMBL4007765 0.82 ALDH1A1 (0.34) NAAAACHEALDH1A1LMNAHPGD
SCHEMBL15028394 0.81 POLB (0.38) GAAMGAMSIMGAM2FAAH
SCHEMBL15806511 0.81 CES2 (0.35) GAAMGAMSIMGAM2FAAH
SCHEMBL15106700 0.81 TSHR (0.36) GAAMGAMSIMGAM2FAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0431324-B1 Pyridine-containing alkoxysilanes bonded to inorganic supports and processes of using the same for removing and concentrating desired ions from solutions UNIV BRIGHAM YOUNG (US) 1994-02-02 EP claimed