Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 1/20 | 0.54 |
| ▸ | PLA2G4B | P0C869 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | PLK1 | P53350 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9325186 | 1.00 | PLA2G2A (0.54) | PLA2G2APLA2G4BLMNAHPGDMEN1 | |
| SCHEMBL9323897 | 1.00 | PLA2G2A (0.54) | PLA2G2APLA2G4BLMNAHPGDMEN1 | |
| SCHEMBL9167382 | 0.96 | PLA2G2A (0.58) | PLA2G2ALMNAHPGDMEN1KMT2A | |
| SCHEMBL31007012 | 0.96 | PLA2G2A (0.58) | PLA2G2ALMNAHPGDMEN1KMT2A | |
| SCHEMBL9327294 | 0.94 | NR4A2 (0.55) | PLA2G2APLA2G4BLMNAHPGDMEN1 | |
| SCHEMBL9323928 | 0.93 | LMNA (0.60) | LMNAHPGDMEN1KMT2ANPC1 | |
| SCHEMBL9323915 | 0.89 | PLA2G2A (0.56) | PLA2G2APLA2G4BMEN1KMT2ATP53 | |
| SCHEMBL9325248 | 0.89 | PLA2G2A (0.70) | PLA2G2APLA2G4BMEN1KMT2ATP53 | |
| SCHEMBL9325267 | 0.89 | PLA2G2A (0.70) | PLA2G2APLA2G4BMEN1KMT2ATP53 | |
| SCHEMBL9324878 | 0.89 | PLA2G2A (0.70) | PLA2G2APLA2G4BMEN1KMT2ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-6092936-A | — | — | None | — | — | JP | disclosed |
| US-5374772-A | Skin disorders, antiinflammatory agents, cardiovascular disorders | HOFFMANN-LAROCHE INC. (US) | 1994-12-20 | — | — | US | disclosed |
| EP-0601385-A1 | Disubstituted benzoic acid derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1994-06-15 | — | — | EP | disclosed |
| JP-H0692936-A | PYRIDYLOXY-NAPHTHALENES | BAYER AG | 1994-04-05 | — | — | JP | disclosed |