Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMARCA2 | P51531 | 6/20 | 0.43 |
| ▸ | SMARCA4 | P51532 | 5/20 | 0.43 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | RIOK2 | Q9BVS4 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.37 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.37 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.37 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | PRKACA | P17612 | 1/20 | 0.36 |
| ▸ | CCR1 | P32246 | 1/20 | 0.36 |
| ▸ | CCR5 | P51681 | 1/20 | 0.36 |
| ▸ | CCR8 | P51685 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2860423 | 0.82 | LMNA (0.46) | SMARCA2SMARCA4RECQLCYP11B1CYP11B2 | |
| SCHEMBL2549948 | 0.82 | CCR1 (0.57) | RIOK2ALDH1A1CCR1CCR5CCR8 | |
| SCHEMBL9326916 | 0.82 | KMT2A (0.44) | SMARCA2SMARCA4RECQLALDH1A1 | |
| SCHEMBL9568958 | 0.81 | AAK1 (0.38) | RIOK2ALDH1A1AAK1CCR1CCR5 | |
| SCHEMBL9650144 | 0.80 | RECQL (0.41) | SMARCA2SMARCA4NFE2L2RECQLGRM5 | |
| SCHEMBL9319785 | 0.80 | RECQL (0.41) | SMARCA2SMARCA4NFE2L2RECQLGRM5 | |
| SCHEMBL7167241 | 0.79 | NOS3 (0.59) | ROCK1ROCK2AAK1CYP3A4PRKACA | |
| SCHEMBL27572847 | 0.79 | SMARCA2 (0.40) | SMARCA2SMARCA4GRM5ALDH1A1AAK1 | |
| SCHEMBL15880529 | 0.79 | MEN1 (0.52) | SMARCA2SMARCA4NFE2L2RECQLGRM5 | |
| SCHEMBL15357773 | 0.78 | ALDH1A1 (0.39) | SMARCA2SMARCA4NFE2L2RECQLALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0438691-B1 | Process for the preparation of substituted 2-chloropyridines | BAYER AG (DE) | 1994-02-16 | — | — | EP | disclosed |
| EP-0438691-A1 | Process for the preparation of substituted 2-chloropyridines | BAYER AG (DE) | 1991-07-31 | — | — | EP | disclosed |
| EP-0370317-A1 | Process for the preparation of substituted 2-chloropyridines | BAYER AG (DE) | 1990-05-30 | — | — | EP | disclosed |