Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINE1 | P05121 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NUDT1 | P36639 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15892076 | 0.82 | SERPINE1 (0.33) | SERPINE1 | |
| SCHEMBL21143363 | 0.82 | ADRA2A (0.38) | SERPINE1 | |
| SCHEMBL13380218 | 0.82 | MGAM (0.44) | SERPINE1KDM4E | |
| SCHEMBL17746187 | 0.81 | MGAM (0.44) | SERPINE1KDM4E | |
| SCHEMBL27853451 | 0.80 | NAAA (0.39) | SERPINE1LMNAHSD17B10KDM4ENUDT1 | |
| SCHEMBL1851945 | 0.79 | LMNA (0.34) | LMNAHSD17B10KDM4E | |
| SCHEMBL1468348 | 0.78 | TSHR (0.41) | SERPINE1HSD17B10 | |
| SCHEMBL21143386 | 0.78 | TSHR (0.41) | LMNAKDM4E | |
| SCHEMBL8997470 | 0.78 | CYP4F2 (0.32) | SERPINE1 | |
| SCHEMBL274635 | 0.78 | DGKA (0.42) | LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3596064-B1 | TOSYLACETATE BASED COMPOUNDS AND DERIVATIVES THEREOF AS PHGDH INHIBITORS | BOEHRINGER INGELHEIM INT (DE) | 2021-03-03 | — | — | EP | disclosed |
| US-5324706-A | Improved adhesion between support and dye layer; thermostability | AGFA-GEVAERT, N.V. (BE) | 1994-06-28 | — | — | US | disclosed |