Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 6/20 | 0.40 |
| ▸ | CNR1 | P21554 | 2/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 3/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | HTR1D | P28221 | 1/20 | 0.34 |
| ▸ | HTR1B | P28222 | 1/20 | 0.34 |
| ▸ | HTR1F | P30939 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | ICMT | O60725 | 3/20 | 0.34 |
| ▸ | NQO2 | P16083 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6111306 | 0.77 | ALOX5 (0.49) | ALOX5HTR6ICMTPOLB | |
| SCHEMBL11346807 | 0.76 | TBXAS1 (0.52) | POLB | |
| SCHEMBL11825251 | 0.73 | MAPT (0.47) | POLB | |
| SCHEMBL15374348 | 0.71 | SCN9A (0.54) | CNR2CNR1ICMT | |
| SCHEMBL28010974 | 0.68 | CNR2 (0.43) | PLA2G2ACNR2CNR1 | |
| SCHEMBL4446113 | 0.68 | GABRA1 (0.50) | CNR2CNR1GABRA1GABRB2ALOX5 | |
| SCHEMBL2503422 | 0.67 | GABRA1 (0.46) | CNR2CNR1GABRA1GABRB2ALOX5 | |
| SCHEMBL29092494 | 0.67 | ALDH1A1 (0.48) | PLA2G2AHTR6ICMTPOLB | |
| SCHEMBL1520654 | 0.67 | ALOX5 (0.52) | ALOX5HTR6ICMTPOLB | |
| SCHEMBL28672344 | 0.67 | HTR6 (0.46) | PLA2G2AHTR6HTR1AHTR1DHTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0582977-A1 | Process for the preparation of 1,3-dialkyl-5-hydroxyoxindoles and of their ether derivatives | BOEHRINGER INGELHEIM KG (DE) | 1994-02-16 | — | — | EP | disclosed |