SCHEMBL9325847

SCHEMBL9325847

CC(C)[C@H](NC(=O)[C@H](C)NC(=O)OCc1ccccc1)C(=O)O

nearest known ligand 0.62

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ECE1 P42892 4/20 0.62
MME P08473 4/20 0.62
CTSK P43235 7/20 0.58
CTSB P07858 4/20 0.55
ELANE P08246 1/20 0.54
CTSL P07711 3/20 0.54
CTSS P25774 3/20 0.54
MEN1 O00255 1/20 0.54
LMNA P02545 1/20 0.54
KMT2A Q03164 1/20 0.54
CYP1A2 P05177 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9574224 1.00 ECE1 (0.62) ECE1MMECTSKCTSBELANE
SCHEMBL7378851 0.90 ECE1 (0.64) ECE1MMECTSKCTSBCTSL
SCHEMBL6272667 0.90 ECE1 (0.64) ECE1MMECTSKCTSBCTSL
SCHEMBL8671882 0.90 CTSL (0.63) ECE1MMECTSKCTSBELANE
SCHEMBL2978398 0.90 CTSL (0.63) ECE1MMECTSKCTSBELANE
SCHEMBL220569 0.90 CTSL (0.63) ECE1MMECTSKCTSBELANE
SCHEMBL1287168 0.90 CTSL (0.63) ECE1MMECTSKCTSBELANE
SCHEMBL30748713 0.88 CTSK (0.65) CTSKCTSBELANECTSLCTSS
SCHEMBL29576918 0.88 CTSB (0.64) ECE1MMECTSKCTSBCTSL
SCHEMBL10980641 0.88 CTSK (0.53) ECE1MMECTSKCTSBELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3994148-A1 PEPTIDE ACETALS FOR STABILISING ENZYMES BASF SE (DE) 2022-05-11 EP claimed
EP-4748846-A1 METHOD FOR SYNTHESIZING AMIDE AND/OR POLYPEPTIDE BY TAKING TRANSIENTLY PROTECTED AMINO ACID AS AMMONIA COMPONENT GUANGZHOU MEDICAL UNIVERSITY (CN) 2026-05-27 EP disclosed
US-20260001907-A1 Method for Synthesizing Amide and/or Polypeptide Using Transient Protected Amino Acid as Ammonia Component UNIV GUANGZHOU MEDICAL (CN) 2026-01-01 US disclosed
CN-119371478-A Method for synthesizing amide and/or polypeptide by taking transient protection amino acid as ammonia component 广州医科大学 2025-01-28 CN disclosed
WO-2025015659-A1 METHOD FOR SYNTHESIZING AMIDE AND/OR POLYPEPTIDE BY TAKING TRANSIENTLY PROTECTED AMINO ACID AS AMMONIA COMPONENT 广州医科大学 2025-01-23 WO disclosed
US-11946079-B2 Method for producing a protein hydrolysate using an endopeptidase and a carboxypeptidase NOVOZYMES A/S (DK) 2024-04-02 US disclosed
US-20220127592-A1 POLYPEPTIDE, USE AND METHOD FOR HYDROLYSING PROTEIN NOVOZYMES A/S (DK) 2022-04-28 US disclosed
EP-0321722-B1 Process for obtaining dipeptides DEGUSSA (DE) 1994-02-16 EP disclosed
US-5216125-A Active ester used for production of acylated amino acids SANSHIN KAGAKU KOGYO CO. LTD. (JP) 1993-06-01 US disclosed
US-5117031-A ACTIVE ESTERS USED FOR PRODUCTION OF ESTERS OR AMIDES AND PROCESS FOR PRODUCING ESTERS OR AMIDES SANSHIN KAGAKU KOGYO CO. LTD. (JP) 1992-05-26 US disclosed
EP-0226304-B1 COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC SANKYO COMPANY LIMITED (JP) 1991-08-28 EP disclosed
EP-0245662-B1 P-HYDROXYPHENYLSULFONIUM SALTS AND THEIR USE IN THE PREPARATION OF ESTERS AND AMIDES SANSHIN KAGAKU KOGYO CO., LTD. (JP) 1991-08-07 EP disclosed
EP-0331988-A1 Sulfonium compounds, as well as process for producing active esters and amides used for the production of amides SANSHIN KAGAKU KOGYO CO., LTD. (JP) 1989-09-13 EP disclosed
US-4857656-A Active esters used for production of esters or amides and process for producing esters or amides SANSHIN KAGAKU KOGYO CO., LTD. (JP) 1989-08-15 US disclosed
EP-0321722-A2 Process for obtaining dipeptides Degussa Aktiengesellschaft (DE) 1989-06-28 EP disclosed
US-4757066-A Reduces renal toxicity SANKYO COMPANY LIMITED (JP) 1988-07-12 US disclosed
EP-0245662-A1 p-Hydroxyphenylsulfonium salts and their use in the preparation of esters and amides SANSHIN KAGAKU KOGYO CO., LTD. (JP) 1987-11-19 EP disclosed
EP-0226304-A1 Composition containing a penem or carbapenem antibiotic SANKYO COMPANY LIMITED (JP) 1987-06-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260001907-A1 Method for Synthesizing Amide and/or Polypeptide Using Transient Protected Amino Acid as Ammonia Component BCAT1, BCAT2, VIP ECE1 2198/4885MME 1938/4885CTSK 842/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.