Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 6/20 | 0.46 |
| ▸ | BCHE | P06276 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9326920 | 0.83 | MEN1 (0.57) | RAB9ALMNASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL2860423 | 0.81 | LMNA (0.46) | RAB9ALMNASMN1; SMN2ACHEKMT2A | |
| SCHEMBL26986519 | 0.80 | RAB9A (0.53) | RAB9ALMNASMN1; SMN2NCEH1ACHE | |
| SCHEMBL9650144 | 0.79 | RECQL (0.41) | ALDH1A1CYP11B1CYP11B2 | |
| SCHEMBL9319785 | 0.79 | RECQL (0.41) | KDM4EALDH1A1CYP11B1CYP11B2 | |
| SCHEMBL9324832 | 0.78 | SMARCA2 (0.43) | ALDH1A1CYP11B1CYP11B2 | |
| SCHEMBL26780462 | 0.78 | RAB9A (0.50) | RAB9ALMNASMN1; SMN2NCEH1ACHE | |
| SCHEMBL15880529 | 0.77 | MEN1 (0.52) | KMT2AMEN1KDM4ECYP11B1CYP11B2 | |
| SCHEMBL27703246 | 0.77 | ELANE (0.49) | — | |
| SCHEMBL27680292 | 0.77 | ACHE (0.46) | RAB9ASMN1; SMN2ACHEKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0438691-B1 | Process for the preparation of substituted 2-chloropyridines | BAYER AG (DE) | 1994-02-16 | — | — | EP | disclosed |
| EP-0438691-A1 | Process for the preparation of substituted 2-chloropyridines | BAYER AG (DE) | 1991-07-31 | — | — | EP | disclosed |
| EP-0370317-A1 | Process for the preparation of substituted 2-chloropyridines | BAYER AG (DE) | 1990-05-30 | — | — | EP | disclosed |