Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 13/20 | 0.37 |
| ▸ | CES1 | P23141 | 8/20 | 0.37 |
| ▸ | CES2 | O00748 | 5/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | PLA2G4C | Q9UP65 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9766947 | 0.85 | GPR84 (0.42) | MAPT | |
| SCHEMBL9766991 | 0.81 | F10 (0.37) | FAAHALDH1A1 | |
| SCHEMBL9326801 | 0.78 | EPHX1 (0.37) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL9767154 | 0.76 | ALDH2 (0.31) | CYP1A2 | |
| SCHEMBL9766905 | 0.76 | GPR84 (0.31) | — | |
| SCHEMBL7301168 | 0.75 | CA2 (0.40) | MEN1CYP1A2KMT2AALDH1A1BLM | |
| SCHEMBL7303995 | 0.75 | CA2 (0.40) | MEN1CYP1A2KMT2AALDH1A1BLM | |
| SCHEMBL9671129 | 0.75 | CA2 (0.40) | MEN1CYP1A2KMT2AALDH1A1BLM | |
| SCHEMBL9671527 | 0.75 | CA2 (0.40) | MEN1CYP1A2KMT2AALDH1A1BLM | |
| SCHEMBL9325177 | 0.72 | ALDH1A1 (0.39) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5013850-A | 4-ethyl and 4-ethenyl-5-hydroxy-2(5H)-furanones substituted on alpha carbon of the ethyl or ethenyl side chain with a long chain alkyl group and on the beta carbon with a polar group, as anti-inflammatory agents | ALLERGAN, INC. (US) | 1991-05-07 | — | — | US | disclosed |