Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.50 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.42 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.42 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13220411 | 0.86 | GABRA1 (0.60) | GABRA1GABRB2TSHRALDH1A1CYP1A2 | |
| SCHEMBL51565 | 0.82 | GABRA1 (0.71) | GABRA1GABRB2TSHRALDH1A1CYP1A2 | |
| SCHEMBL29440398 | 0.82 | GABRA1 (0.71) | GABRA1GABRB2TSHRALDH1A1CYP1A2 | |
| SCHEMBL13596606 | 0.79 | TRPA1 (0.54) | GABRA1GABRB2TSHRALDH1A1CYP1A2 | |
| SCHEMBL2047945 | 0.78 | GABRA1 (0.70) | GABRA1GABRB2TSHRALDH1A1CYP1A2 | |
| SCHEMBL7786826 | 0.78 | HPGD (0.54) | GABRA1GABRB2TSHRALDH1A1CYP1A2 | |
| SCHEMBL19779505 | 0.76 | TSHR (0.57) | GABRA1GABRB2TSHRALDH1A1CYP1A2 | |
| SCHEMBL28490762 | 0.75 | LMNA (0.50) | GABRA1GABRB2TSHRALDH1A1CYP3A4 | |
| SCHEMBL16328212 | 0.75 | CA2 (0.53) | GABRA1GABRB2TSHRALDH1A1CYP1A2 | |
| 2-Chlorophenol SCHEMBL8466384 | 0.75 | GABRA1 (0.75) | GABRA1GABRB2TSHRALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0403026-B1 | 12-Substituted-12H-dibenzo(D,G)(1,3)dioxocin-6-carboxylic acids, herbicidal compositions, and a method of controlling undesirable vegetation | DOWELANCO (US) | 1994-03-02 | — | — | EP | disclosed |
| US-5158597-A | Herbicidal 12-substituted 12H-dibenzo[d,g]dioxocin-6-carboxylic acids | THE DOW CHEMICAL COMPANY (US) | 1992-10-27 | — | — | US | disclosed |
| US-5071465-A | Preemergence; postemergence | THE DOW CHEMICAL COMPANY (US) | 1991-12-10 | — | — | US | disclosed |
| US-4999448-A | ALKYLATION WITH PHENYLTHIOMETHYL LITHIUM COMPOUND, CYCLIZATION, INTERMEDIATES FOR HERBICIDES | THE DOW CHEMICAL COMPANY (US) | 1991-03-12 | — | — | US | disclosed |
| EP-0403026-A1 | 12-Substituted-12H-dibenzo(D,G)(1,3)dioxocin-6-carboxylic acids, herbicidal compositions, and a method of controlling undesirable vegetation | DowElanco (US) | 1990-12-19 | — | — | EP | disclosed |
| US-4938790-A | Herbicidal 12-substituted 12H-dibenzo(D,G)(1,3)dioxocin-6-carboxylic acids | THE DOW CHEMICAL COMPANY (US) | 1990-07-03 | — | — | US | disclosed |