Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL952881 | 0.81 | ALDH1A1 (0.35) | — | |
| SCHEMBL9469719 | 0.70 | CYP3A4 (0.33) | OPRM1OPRK1CYP3A4CASP1RECQL | |
| SCHEMBL6573456 | 0.68 | TSHR (0.35) | OPRM1OPRK1 | |
| SCHEMBL10184984 | 0.68 | CYP3A4 (0.46) | OPRM1OPRK1CYP3A4CASP1RECQL | |
| SCHEMBL2048189 | 0.67 | OPRM1 (0.33) | OPRM1OPRK1 | |
| SCHEMBL2232620 | 0.65 | OPRM1 (0.34) | OPRM1OPRK1 | |
| SCHEMBL23748537 | 0.65 | OPRM1 (0.32) | OPRM1OPRK1 | |
| SCHEMBL3212086 | 0.64 | TSHR (0.41) | OPRM1OPRK1CYP3A4CASP1RECQL | |
| SCHEMBL29841314 | 0.64 | TSHR (0.41) | OPRM1OPRK1CYP3A4CASP1RECQL | |
| SCHEMBL8018743 | 0.64 | OPRL1 (0.33) | OPRM1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5286890-A | Aromatic amine terminated silicone monomers, oligomers, and polymers therefrom | HUGHES AIRCRAFT COMPANY (US) | 1994-02-15 | — | — | US | disclosed |