Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 3/20 | 0.37 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.30 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.30 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12978332 | 0.77 | ALDH1A1 (0.34) | GPBAR1 | |
| SCHEMBL2374866 | 0.72 | MLNR (0.34) | — | |
| SCHEMBL932926 | 0.67 | MAPT (0.40) | TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL16660723 | 0.67 | KMT2A (0.38) | — | |
| SCHEMBL23062875 | 0.66 | TAS1R3 (0.33) | TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL20542388 | 0.66 | ROCK2 (0.38) | GPBAR1 | |
| SCHEMBL16660728 | 0.66 | KMT2A (0.38) | — | |
| SCHEMBL20305332 | 0.66 | LMNA (0.41) | TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL16660727 | 0.65 | KMT2A (0.36) | — | |
| SCHEMBL15662045 | 0.65 | KMT2A (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8710056-B2 | Pyridazine compounds for controlling invertebrate pests | BASF SE (DE) | 2014-04-29 | — | — | US | disclosed |
| EP-2451808-B1 | PYRIDAZINE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS | BASF SE (DE) | 2014-03-26 | — | — | EP | disclosed |
| EP-2451808-A1 | PYRIDAZINE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS | BASF SE (DE) | 2012-05-16 | — | — | EP | disclosed |
| US-20120110705-A1 | Pyridazine Compounds for Controlling Invertebrate Pests | BASF SE (DE) | 2012-05-03 | — | — | US | disclosed |
| WO-2011003793-A1 | PYRIDAZINE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS | BASF SE (DE) | 2011-01-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120110705-A1 | Pyridazine Compounds for Controlling Invertebrate Pests | CNR2, GRIN2C, GRIN2A | GPBAR1 1654/4885TAS1R3 3441/4885TAS1R1 3510/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.