Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 5/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | XBP1 | P17861 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | SYK | P43405 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.35 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9326565 | 0.89 | CTSK (0.39) | CTSKMAPTXBP1NPSR1TDP1 | |
| SCHEMBL9326544 | 0.84 | CTSK (0.42) | ALDH1A1CTSKMAPTXBP1NPSR1 | |
| SCHEMBL9329333 | 0.82 | CTSB (0.43) | CTSKMAPTXBP1NPSR1TDP1 | |
| SCHEMBL9326476 | 0.81 | MAPT (0.43) | CTSKMAPTXBP1NPSR1TDP1 | |
| SCHEMBL9326520 | 0.81 | CTSK (0.39) | CTSKMAPTXBP1NPSR1TDP1 | |
| SCHEMBL9327794 | 0.80 | RAB9A (0.39) | ALDH1A1CTSKMAPTXBP1NPSR1 | |
| SCHEMBL9327763 | 0.78 | LMNA (0.39) | CTSKMAPTXBP1NPSR1TDP1 | |
| SCHEMBL7373003 | 0.77 | RAB9A (0.41) | CTSKMAPTXBP1NPSR1TDP1 | |
| SCHEMBL5093810 | 0.77 | RAB9A (0.41) | CTSKMAPTXBP1NPSR1TDP1 | |
| SCHEMBL9327719 | 0.77 | CTSK (0.37) | CTSKMAPTXBP1NPSR1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5304549-A | Control or prevention of degenerative joint diseases | HOFFMANN-LA ROCHE INC. (US) | 1994-04-19 | — | — | US | disclosed |
| EP-0497192-A2 | Amino acid derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1992-08-05 | — | — | EP | disclosed |