Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.33 |
| ▸ | VCP | P55072 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 2/20 | 0.30 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.30 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.30 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.30 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9329023 | 0.92 | VCP (0.32) | UTS2RVCPHTR1AADRA1DADRA1A | |
| SCHEMBL9012178 | 0.89 | ADRA1D (0.34) | UTS2RHTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL9011932 | 0.89 | PDE3B (0.32) | UTS2RPDE3BPDE3A | |
| SCHEMBL9011980 | 0.88 | ADRA1D (0.38) | UTS2RVCPHTR1AADRA1DADRA1A | |
| SCHEMBL9011952 | 0.86 | UTS2R (0.37) | UTS2RVCPADRA1A | |
| SCHEMBL9012410 | 0.83 | HTR1A (0.32) | UTS2RHTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL9327590 | 0.79 | TAAR1 (0.36) | UTS2RVCPHTR1AADRA1DADRA1A | |
| SCHEMBL9329176 | 0.78 | ADRA1D (0.40) | UTS2RHTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL9360746 | 0.77 | UTS2R (0.34) | UTS2RVCPHTR1AADRA1DADRA1A | |
| SCHEMBL9329085 | 0.76 | VCP (0.32) | VCPADRA1DADRA1AADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5523317-A | ADMINISTERING IMIDAZOLE DERIVATIVE | NIPPON CHEMIPHAR CO., LTD. (JP) | 1996-06-04 | — | — | US | disclosed |
| EP-0633026-A1 | Use of imidazole derivative for antihypertensive agent | NIPPON CHEMIPHAR CO., LTD. (JP) | 1995-01-11 | — | — | EP | disclosed |
| EP-0412529-B1 | Imidazole derivatives, process for the preparation of the same and antiulcer agents containing the same | NIPPON CHEMIPHAR CO (JP) | 1994-03-09 | — | — | EP | disclosed |
| EP-0584588-A1 | Anti-ulcer composition containing imidazole derivative | NIPPON CHEMIPHAR CO., LTD. (JP) | 1994-03-02 | — | — | EP | disclosed |
| US-5091403-A | SULFINYL IMIDAZOLE DERIVATIVES AND ANTIULCER AGENTS CONTAINING THE SAME | NIPPON CHEMIPHAR CO., LTD. (JP) | 1992-02-25 | — | — | US | disclosed |
| EP-0412529-A1 | Imidazole derivatives, process for the preparation of the same and antiulcer agents containing the same | NIPPON CHEMIPHAR CO., LTD. (JP) | 1991-02-13 | — | — | EP | disclosed |