Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 4/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 4/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 3/20 | 0.34 |
| ▸ | VCP | P55072 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | FERMT2 | Q96AC1 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.31 |
| ▸ | HSP90AB1 | P08238 | 4/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | TDP2 | O95551 | 1/20 | 0.31 |
| ▸ | FGB | P02675 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9329176 | 0.91 | ADRA1D (0.40) | ADRA1DADRA1AADRA1BADRA2AADRA2C | |
| SCHEMBL9013449 | 0.88 | UTS2R (0.33) | ADRA1DADRA1AADRA1BHTR1AVCP | |
| SCHEMBL9011932 | 0.87 | PDE3B (0.32) | UTS2RPDE3BPDE3A | |
| SCHEMBL9011952 | 0.84 | UTS2R (0.37) | ADRA1AVCPUTS2R | |
| SCHEMBL9011890 | 0.82 | ADRA1D (0.40) | ADRA1DADRA1AADRA1BADRA2AADRA2C | |
| SCHEMBL9329023 | 0.82 | VCP (0.32) | ADRA1DADRA1AADRA1BHTR1AVCP | |
| SCHEMBL9012178 | 0.79 | ADRA1D (0.34) | ADRA1DADRA1AADRA1BADRA2AADRA2C | |
| SCHEMBL9329085 | 0.77 | VCP (0.32) | ADRA1DADRA1AADRA1BADRA2AADRA2C | |
| SCHEMBL9327590 | 0.76 | TAAR1 (0.36) | ADRA1DADRA1AADRA1BHTR1AVCP | |
| SCHEMBL6475931 | 0.76 | UTS2R (0.40) | ADRA1AALDH1A1KMT2AKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5523317-A | ADMINISTERING IMIDAZOLE DERIVATIVE | NIPPON CHEMIPHAR CO., LTD. (JP) | 1996-06-04 | — | — | US | disclosed |
| EP-0633026-A1 | Use of imidazole derivative for antihypertensive agent | NIPPON CHEMIPHAR CO., LTD. (JP) | 1995-01-11 | — | — | EP | disclosed |
| EP-0584588-A1 | Anti-ulcer composition containing imidazole derivative | NIPPON CHEMIPHAR CO., LTD. (JP) | 1994-03-02 | — | — | EP | disclosed |