Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 2/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 9/20 | 0.35 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8616314 | 0.79 | TBXA2R (0.39) | TBXA2RROCK2TBXAS1ALDH1A1MAPT | |
| SCHEMBL9329616 | 0.78 | TBXAS1 (0.42) | TBXA2RROCK2TBXAS1ALDH1A1MAPT | |
| SCHEMBL8798158 | 0.72 | KMT2A (0.43) | ALDH1A1MAPTNPC1RAB9APOLB | |
| SCHEMBL8797482 | 0.71 | LPAR1 (0.45) | TBXA2RALDH1A1MAPTRAB9ATP53 | |
| SCHEMBL8614659 | 0.70 | TBXAS1 (0.39) | TBXA2RROCK2TBXAS1TP53POLB | |
| SCHEMBL8797449 | 0.69 | LPAR1 (0.44) | TBXA2RALDH1A1MAPTTP53POLB | |
| SCHEMBL8613749 | 0.69 | LPAR1 (0.45) | TBXA2RTBXAS1 | |
| SCHEMBL8620512 | 0.69 | RAB9A (0.41) | TBXAS1ALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL8797662 | 0.68 | LPAR1 (0.46) | TBXA2RALDH1A1TP53SMN1; SMN2MEN1 | |
| SCHEMBL8797675 | 0.67 | HTT (0.43) | TBXA2RMAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0588608-A2 | Tricyclic compounds and pharmaceutical compositions containing them | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1994-03-23 | — | — | EP | disclosed |