Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.64 |
| ▸ | CES1 | P23141 | 2/20 | 0.64 |
| ▸ | CES2 | O00748 | 1/20 | 0.64 |
| ▸ | BCHE | P06276 | 1/20 | 0.64 |
| ▸ | GAA | P10253 | 1/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.64 |
| ▸ | ALDH3A1 | P30838 | 3/20 | 0.57 |
| ▸ | ALDH2 | P05091 | 2/20 | 0.57 |
| ▸ | ACHE | P22303 | 2/20 | 0.49 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.48 |
| ▸ | CUL4A | Q13619 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | TDO2 | P48775 | 1/20 | 0.46 |
| ▸ | IDO2 | Q6ZQW0 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 2/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.45 |
| ▸ | PTPRC | P08575 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | S100A4 | P26447 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29678555 | 1.00 | ALDH1A1 (0.64) | ALDH1A1CES1CES2BCHEGAA | |
| SCHEMBL19537765 | 0.81 | ALDH1A1 (0.43) | ALDH1A1CES1CES2BCHEGAA | |
| SCHEMBL9330155 | 0.80 | ALDH1A1 (0.64) | ALDH1A1CES1CES2BCHEGAA | |
| SCHEMBL2350240 | 0.80 | AGTR1 (0.72) | ALDH1A1CES1CES2BCHEGAA | |
| SCHEMBL13083527 | 0.80 | GAA (0.64) | ALDH1A1CES1CES2BCHEGAA | |
| SCHEMBL30951976 | 0.79 | CES1 (0.73) | ALDH1A1CES1CES2BCHEGAA | |
| SCHEMBL14830299 | 0.79 | CES1 (0.73) | ALDH1A1CES1CES2BCHEGAA | |
| Phenyl Isatin SCHEMBL916808 | 0.78 | CES1 (1.00) | ALDH1A1CES1CES2BCHEGAA | |
| SCHEMBL19537768 | 0.78 | ALDH1A1 (0.49) | ALDH1A1CES1CES2BCHEGAA | |
| SCHEMBL5104501 | 0.77 | ESR1 (0.72) | ALDH1A1NPSR1ESR1ESR2PTPRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11643414-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2023-05-09 | — | — | US | disclosed |
| US-11643414-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2023-05-09 | — | — | US | disclosed |
| US-11643414-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2023-05-09 | — | — | US | disclosed |
| CN-109071580-B | Material for organic electroluminescent device | 默克专利有限公司 | 2022-05-24 | — | — | CN | disclosed |
| EP-3448866-B1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2020-06-17 | — | — | EP | disclosed |
| EP-3448866-B1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2020-06-17 | — | — | EP | disclosed |
| US-20190135814-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2019-05-09 | — | — | US | disclosed |
| US-20190135814-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2019-05-09 | — | — | US | disclosed |
| WO-2017186760-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2017-11-02 | — | — | WO | disclosed |
| WO-2017186760-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2017-11-02 | — | — | WO | disclosed |
| EP-0369344-B1 | N-arylation of isatins | ABBOTT LAB (US) | 1994-04-06 | — | — | EP | disclosed |
| EP-0369344-A1 | N-arylation of isatins | ABBOTT LABORATORIES (US) | 1990-05-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11643414-B2 | Materials for organic electroluminescent devices | SLCO4C1, SLCO2A1, PIEZO1 | ALDH1A1 142/4885CES1 4027/4885CES2 1720/4885 |
| US-20190135814-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | SLCO4C1, SLCO2A1, PIEZO1 | ALDH1A1 136/4885CES1 3948/4885CES2 1404/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.