Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 6/20 | 0.54 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.42 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.40 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9333735 | 0.91 | LPAR1 (0.53) | LPAR1KCNK3KCNK9 | |
| SCHEMBL9333721 | 0.86 | LPAR1 (0.46) | LPAR1 | |
| SCHEMBL7565089 | 0.83 | LMNA (0.48) | — | |
| SCHEMBL9333016 | 0.79 | NLRP3 (0.46) | — | |
| SCHEMBL9330665 | 0.78 | LMNA (0.43) | — | |
| SCHEMBL9333003 | 0.76 | — | — | |
| SCHEMBL9330456 | 0.75 | NLRP3 (0.46) | — | |
| SCHEMBL9138808 | 0.74 | LPAR1 (0.41) | LPAR1 | |
| SCHEMBL9488235 | 0.73 | LPAR1 (0.60) | LPAR1 | |
| SCHEMBL9330682 | 0.71 | RECQL (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5364882-A | Acyloenzyme a: cholesterol acyltransferase inhibitors, anticholesterol | WARNER-LAMBERT COMPANY (US) | 1994-11-15 | — | — | US | disclosed |
| EP-0556308-A1 | OXYSULFONYL UREA ACAT INHIBITORS. | WARNER LAMBERT CO (US) | 1993-08-25 | — | — | EP | disclosed |
| WO-1992008692-A1 | OXYSULFONYL UREA ACAT INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1992-05-29 | — | — | WO | disclosed |