Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9330665 | 0.82 | LMNA (0.43) | — | |
| SCHEMBL7565089 | 0.79 | LMNA (0.48) | — | |
| SCHEMBL9333016 | 0.75 | NLRP3 (0.46) | — | |
| SCHEMBL9333735 | 0.75 | LPAR1 (0.53) | — | |
| SCHEMBL9333003 | 0.72 | — | — | |
| SCHEMBL9330447 | 0.71 | LPAR1 (0.54) | — | |
| SCHEMBL9330456 | 0.71 | NLRP3 (0.46) | — | |
| SCHEMBL9450965 | 0.69 | NLRP3 (0.49) | — | |
| SCHEMBL9333721 | 0.69 | LPAR1 (0.46) | — | |
| SCHEMBL20540474 | 0.68 | KMT2A (0.57) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5364882-A | Acyloenzyme a: cholesterol acyltransferase inhibitors, anticholesterol | WARNER-LAMBERT COMPANY (US) | 1994-11-15 | — | — | US | disclosed |
| US-5198466-A | Acylcoenzyme A Inhibitors | WARNER-LAMBERT COMPANY (US) | 1993-03-30 | — | — | US | disclosed |
| WO-1992008692-A1 | OXYSULFONYL UREA ACAT INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1992-05-29 | — | — | WO | disclosed |