Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7565089 | 0.89 | LMNA (0.48) | LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL9333016 | 0.85 | NLRP3 (0.46) | LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL9333735 | 0.82 | LPAR1 (0.53) | SMN1; SMN2 | |
| SCHEMBL9333003 | 0.82 | — | — | |
| SCHEMBL9330682 | 0.82 | RECQL (0.44) | — | |
| SCHEMBL9330456 | 0.78 | NLRP3 (0.46) | — | |
| SCHEMBL9330447 | 0.78 | LPAR1 (0.54) | — | |
| SCHEMBL9333721 | 0.76 | LPAR1 (0.46) | — | |
| SCHEMBL20540474 | 0.72 | KMT2A (0.57) | LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL7108515 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5364882-A | Acyloenzyme a: cholesterol acyltransferase inhibitors, anticholesterol | WARNER-LAMBERT COMPANY (US) | 1994-11-15 | — | — | US | disclosed |
| WO-1992008692-A1 | OXYSULFONYL UREA ACAT INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1992-05-29 | — | — | WO | disclosed |