SCHEMBL9332173

SCHEMBL9332173

[CH2]Sc1nnnn1CS(N)(=O)=O

nearest known ligand 0.38

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.38
LMNA P02545 1/20 0.36
KMT2A Q03164 1/20 0.36
CYP1A2 P05177 1/20 0.32
NPC1 O15118 2/20 0.30
RAB9A P51151 2/20 0.30
TP53 P04637 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
POLB P06746 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4597740 0.82 KMT2A (0.36) ALDH1A1LMNAKMT2ACYP1A2NPC1
SCHEMBL9332182 0.82 LMNA (0.58) ALDH1A1LMNAKMT2ACYP1A2NPC1
SCHEMBL9703552 0.75
SCHEMBL11502271 0.72 CYP1A2 (0.31) CYP1A2
SCHEMBL9479526 0.71
SCHEMBL11247291 0.67 LMNA (0.38) ALDH1A1LMNAKMT2ACYP1A2
SCHEMBL11687235 0.66 HTT (0.52) ALDH1A1LMNAKMT2ACYP1A2POLB
SCHEMBL9088387 0.65 ALDH1A1 (0.40) ALDH1A1LMNAKMT2ANPC1RAB9A
SCHEMBL3742866 0.64 LMNA (0.48) ALDH1A1LMNAKMT2A
SCHEMBL4597744 0.64 KMT2A (0.58) ALDH1A1LMNAKMT2ACYP1A2NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0289002-B1 Novel cephalosporin compounds and antibacterial agents MEIJI SEIKA KAISHA (JP) 1994-10-26 EP disclosed
EP-0315997-B1 Cephalosporin compounds and antibacterial agents MEIJI SEIKA KAISHA (JP) 1994-04-20 EP disclosed
EP-0209751-B1 CEPHALOSPORIN DERIVATIVES AND BACTERICIDES CONTAINING THE SAME MEIJI SEIKA KAISHA LTD. (JP) 1992-09-16 EP disclosed
US-5028601-A Substituted with an amino thiazole group and a dihydroxy-pyridone group MEIJI SAIKA KAISHA, LTD. (JP) 1991-07-02 US disclosed
US-4971961-A ANTIBIOTICS AS BACTERICIDES AGAINST PSEUDOMONAS MEIJI SEIKA KAISHA, LTD. (JP) 1990-11-20 US disclosed
EP-0315997-A2 Cephalosporin compounds and antibacterial agents MEIJI SEIKA KAISHA LTD. (JP) 1989-05-17 EP disclosed
EP-0289002-A2 Novel cephalosporin compounds and antibacterial agents MEIJI SEIKA KAISHA LTD. (JP) 1988-11-02 EP disclosed
US-4758557-A Cephalosporin derivatives and bactericides containing the same MEIJI SEIKA KAISHA, LTD. (JP) 1988-07-19 US disclosed
EP-0209751-A2 Cephalosporin derivatives and bactericides containing the same MEIJI SEIKA KAISHA LTD. (JP) 1987-01-28 EP disclosed