Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9334609 | 0.83 | KMT2A (0.65) | KMT2ALMNAALDH1A1HSD17B10HTT | |
| SCHEMBL13297834 | 0.83 | ALDH1A1 (0.47) | KMT2ALMNAALDH1A1HSD17B10HTT | |
| SCHEMBL9332182 | 0.82 | LMNA (0.58) | KMT2ALMNAALDH1A1HSD17B10HTT | |
| SCHEMBL4597740 | 0.82 | KMT2A (0.36) | KMT2ALMNAALDH1A1HSD17B10HTT | |
| SCHEMBL16118721 | 0.80 | ALDH1A1 (0.53) | KMT2ALMNAALDH1A1HSD17B10HTT | |
| SCHEMBL16091099 | 0.79 | HSD17B10 (0.43) | KMT2ALMNAALDH1A1HSD17B10HTT | |
| SCHEMBL9487028 | 0.76 | KMT2A (0.59) | KMT2ALMNAALDH1A1HSD17B10HTT | |
| SCHEMBL10404026 | 0.76 | ALDH1A1 (0.37) | KMT2ALMNAALDH1A1HSD17B10HTT | |
| SCHEMBL13814463 | 0.74 | LMNA (0.31) | KMT2ALMNA | |
| SCHEMBL9602660 | 0.70 | CYP1A2 (0.31) | CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6420554-B1 | REACTION OF BETA LACTAM WITH PHOSPHOROUS HALIDE IN THE PRESENCE OF BASE, ADDING PHENOL, REACTION WITH ALCOHOL AND REMOVAL OF ESTER | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 2002-07-16 | — | — | US | claimed |
| US-4547573-A | BACTERICIDES | ICI PHARMA (FR) | 1985-10-15 | — | — | US | claimed |
| US-4504478-A | Cephalosporin-1-oxide derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (FR) | 1985-03-12 | — | — | US | claimed |
| US-4497949-A | PHOTOTHERMOGRAPHY;COLOR FILMS;STORAGE STABILITY;ANTIFOGGING AGENTS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1985-02-05 | — | — | US | claimed |
| US-4492692-A | BACTERICIDE | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1985-01-08 | — | — | US | claimed |
| US-4463173-A | ANTIBIOTIC, BACTERICIDE | ICI PHARMA (FR) | 1984-07-31 | — | — | US | claimed |
| EP-0113965-A2 | Process for the preparation of cephalosporin derivatives | ICI PHARMA (FR) | 1984-07-25 | — | — | EP | claimed |
| EP-0031708-B1 | CEPHALOSPORIN DERIVATIVES, PROCESSES FOR THEIR MANUFACTURE, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND INTERMEDIATES THEREFOR | ICI PHARMA (FR) | 1984-06-13 | — | — | EP | claimed |
| EP-0082648-A2 | Cephalosporin derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1983-06-29 | — | — | EP | claimed |
| EP-0075434-A2 | Cephalosporins, their preparation and their pharmaceutical compositions | ICI PHARMA (FR) | 1983-03-30 | — | — | EP | claimed |
| EP-0072608-A2 | Process for the preparation of cephalosporin derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1983-02-23 | — | — | EP | claimed |
| EP-0055562-A2 | Cephalosporin derivatives | ICI PHARMA (FR) | 1982-07-07 | — | — | EP | claimed |
| EP-1010701-B1 | PROCESS FOR THE PREPARATION OF 3-CEPHEM COMPOUNDS | OTSUKA KAGAKU KK (JP) | 2008-01-16 | — | — | EP | disclosed |
| US-20070196859-A1 | Novel antibacterial agents | THERAVANCE BIOPHARMA ANTIBIOTICS IP, LLC | 2007-08-23 | — | — | US | disclosed |
| US-20070111980-A1 | Process for preparing pure cephalosporine intermediates | HETERO DRUGS LIMITED (IN) | 2007-05-17 | — | — | US | disclosed |
| WO-2004101572-A1 | 7-GLUTARYL IMIDE CEPHALOSPORANIC ACID DERIVATIVES AND PROCESS FOR PREPARING IT | CKD BIO CORPORATION (KR) | 2004-11-25 | — | — | WO | disclosed |
| EP-0075434-A2 | Cephalosporins, their preparation and their pharmaceutical compositions | ICI PHARMA (FR) | 1983-03-30 | — | — | EP | disclosed |
| EP-0072608-A2 | Process for the preparation of cephalosporin derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1983-02-23 | — | — | EP | disclosed |
| EP-0055562-A2 | Cephalosporin derivatives | ICI PHARMA (FR) | 1982-07-07 | — | — | EP | disclosed |
| EP-0031708-A2 | Cephalosporin derivatives, processes for their manufacture, pharmaceutical compositions containing them and intermediates therefor | ICI PHARMA (FR) | 1981-07-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070196859-A1 | Novel antibacterial agents | ENGASE, PEPD, PGLS | KMT2A 3557/4885LMNA 3455/4885ALDH1A1 1953/4885 |
| US-20070111980-A1 | Process for preparing pure cephalosporine intermediates | ACMSD, CEL, MGAM | KMT2A 690/4885LMNA 1502/4885ALDH1A1 197/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.