SCHEMBL9332182

SCHEMBL9332182

CSc1nnnn1CS(N)(=O)=O

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.58
KMT2A Q03164 2/20 0.58
ALDH1A1 P00352 6/20 0.42
NPC1 O15118 2/20 0.33
RAB9A P51151 2/20 0.33
POLB P06746 1/20 0.33
HSD17B10 Q99714 1/20 0.33
CYP1A2 P05177 1/20 0.32
CA12 O43570 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA9 Q16790 1/20 0.32
CYP2C19 P33261 1/20 0.31
HTT P42858 3/20 0.31
HPGD P15428 1/20 0.31
USP2 O75604 1/20 0.31
MEN1 O00255 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
SMN1; SMN2 Q16637 2/20 0.30
TP53 P04637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4597744 0.82 KMT2A (0.58) LMNAKMT2AALDH1A1NPC1RAB9A
SCHEMBL9332173 0.82 ALDH1A1 (0.38) LMNAKMT2AALDH1A1NPC1RAB9A
SCHEMBL11069089 0.77
SCHEMBL9334609 0.72 KMT2A (0.65) LMNAKMT2AALDH1A1HSD17B10CYP1A2
SCHEMBL11502271 0.72 CYP1A2 (0.31) CYP1A2
SCHEMBL11689714 0.69 KMT2A (0.80) LMNAKMT2AALDH1A1NPC1RAB9A
SCHEMBL4597345 0.69 KMT2A (0.80) LMNAKMT2AALDH1A1HSD17B10CYP1A2
SCHEMBL9487028 0.69 KMT2A (0.59) LMNAKMT2AALDH1A1HSD17B10CYP2C19
SCHEMBL11692007 0.68 LMNA (0.64) LMNAKMT2AALDH1A1POLBHSD17B10
SCHEMBL10985420 0.68 KMT2A (0.77) LMNAKMT2AALDH1A1POLBHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0289002-B1 Novel cephalosporin compounds and antibacterial agents MEIJI SEIKA KAISHA (JP) 1994-10-26 EP disclosed
EP-0315997-B1 Cephalosporin compounds and antibacterial agents MEIJI SEIKA KAISHA (JP) 1994-04-20 EP disclosed
EP-0209751-B1 CEPHALOSPORIN DERIVATIVES AND BACTERICIDES CONTAINING THE SAME MEIJI SEIKA KAISHA LTD. (JP) 1992-09-16 EP disclosed
US-5028601-A Substituted with an amino thiazole group and a dihydroxy-pyridone group MEIJI SAIKA KAISHA, LTD. (JP) 1991-07-02 US disclosed
US-4971961-A ANTIBIOTICS AS BACTERICIDES AGAINST PSEUDOMONAS MEIJI SEIKA KAISHA, LTD. (JP) 1990-11-20 US disclosed
EP-0315997-A2 Cephalosporin compounds and antibacterial agents MEIJI SEIKA KAISHA LTD. (JP) 1989-05-17 EP disclosed
EP-0289002-A2 Novel cephalosporin compounds and antibacterial agents MEIJI SEIKA KAISHA LTD. (JP) 1988-11-02 EP disclosed
US-4758557-A Cephalosporin derivatives and bactericides containing the same MEIJI SEIKA KAISHA, LTD. (JP) 1988-07-19 US disclosed
EP-0209751-A2 Cephalosporin derivatives and bactericides containing the same MEIJI SEIKA KAISHA LTD. (JP) 1987-01-28 EP disclosed