Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11247305 | 0.81 | KMT2A (0.62) | LMNAKMT2AALDH1A1CYP1A2 | |
| SCHEMBL11116878 | 0.78 | ALDH1A1 (0.42) | LMNAKMT2AALDH1A1 | |
| SCHEMBL9479526 | 0.74 | — | — | |
| SCHEMBL10475166 | 0.71 | LMNA (0.48) | LMNAKMT2AALDH1A1CYP1A2 | |
| SCHEMBL11689701 | 0.71 | KMT2A (0.53) | LMNAKMT2AALDH1A1CYP1A2 | |
| SCHEMBL13638133 | 0.69 | — | — | |
| SCHEMBL11076123 | 0.69 | — | — | |
| SCHEMBL10792969 | 0.69 | LMNA (0.38) | LMNAKMT2AALDH1A1CYP1A2 | |
| SCHEMBL3742866 | 0.67 | LMNA (0.48) | LMNAKMT2AALDH1A1 | |
| SCHEMBL10189375 | 0.65 | GHSR (0.33) | LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0048168-A2 | 7-Acylamino cephalosporin compounds, their preparation and pharmaceutical formulations containing them | ELI LILLY AND COMPANY (US) | 1982-03-24 | — | — | EP | disclosed |