Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP12 | P39900 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1758414 | 0.79 | PTGDR2 (0.46) | HPGDAKR1B1ABCB11LMNAPTGS1 | |
| SCHEMBL29661155 | 0.79 | PTGDR2 (0.46) | HPGDAKR1B1ABCB11LMNAPTGS1 | |
| SCHEMBL8631418 | 0.75 | POLB (0.53) | CYP2C9HPGDCYP2C19AKR1B1TDP1 | |
| SCHEMBL11006463 | 0.74 | CYP2C9 (0.60) | CYP2C9HPGDCYP2C19AKR1B1ABCB11 | |
| SCHEMBL9334127 | 0.73 | ALDH1A1 (0.39) | PTGDR2SLC6A2SLC6A4MEN1KMT2A | |
| SCHEMBL9334134 | 0.73 | ALDH1A1 (0.39) | PTGDR2SLC6A2SLC6A4MEN1KMT2A | |
| SCHEMBL10424596 | 0.73 | CYP1A2 (0.59) | CYP2C9HPGDCYP2C19AKR1B1ABCB11 | |
| SCHEMBL8229735 | 0.73 | CYP2C9 (0.72) | CYP2C9HPGDCYP2C19AKR1B1ABCB11 | |
| SCHEMBL28320871 | 0.72 | SMN1; SMN2 (0.45) | CYP2C9HPGDCYP2C19LMNASLC6A2 | |
| SCHEMBL286410 | 0.72 | AKR1B1 (0.61) | AKR1B1PTGS2TDP1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0594573-A1 | PREPARATION OF PROPENOIC ACID DERIVATIVES | AgrEvo UK Limited (GB) | 1994-05-04 | — | — | EP | disclosed |
| US-5264609-A | Etherification and hydrolysis | SCHERING AGROCHEMICALS LIMITED (GB) | 1993-11-23 | — | — | US | disclosed |
| WO-1991007385-A1 | PREPARATION OF PROPENOIC ACID DERIVATIVES | SCHERING AGROCHEMICALS LIMITED (GB) | 1991-05-30 | — | — | WO | disclosed |