SCHEMBL9333398

SCHEMBL9333398

NNC(=O)[N]Cc1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.43
GRIN1 Q05586 4/20 0.42
GRIN2B Q13224 4/20 0.42
GRIN2D O15399 2/20 0.42
GRIN3B O60391 2/20 0.42
GRIN2A Q12879 2/20 0.42
GRIN2C Q14957 2/20 0.42
GRIN3A Q8TCU5 2/20 0.42
SIGMAR1 Q99720 2/20 0.42
NOS2 P35228 1/20 0.41
GAA P10253 2/20 0.40
IDO1 P14902 1/20 0.40
CES2 O00748 1/20 0.40
CES1 P23141 1/20 0.40
AKR1B1 P15121 1/20 0.40
SCN2A Q99250 1/20 0.40
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
HDAC8 Q9BY41 1/20 0.39
HDAC6 Q9UBN7 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1455013 0.80 LMNA (0.41) NOS2CES2CES1AKR1B1SCN2A
SCHEMBL6827026 0.79 NOS2 (0.42) GRIN1GRIN2BGRIN2DGRIN3BGRIN2A
SCHEMBL1385743 0.78 EPHX2 (0.53) GAAMEN1KMT2AMAPTKDM4E
SCHEMBL689470 0.77 GRIN2B (0.50) GRIN1GRIN2BGRIN2DGRIN3BGRIN2A
SCHEMBL2500288 0.76 CES2 (0.48) GRIN1GRIN2BNOS2CES2CES1
SCHEMBL1040588 0.72 NOS2 (0.50) GRIN1GRIN2BNOS2CES2CES1
SCHEMBL2096553 0.72 ALDH1A1 (0.42) NOS2CES2CES1AKR1B1SCN2A
SCHEMBL3240431 0.71 GRIN1 (0.48) GRIN1GRIN2BCES2CES1AKR1B1
SCHEMBL8013340 0.71 CES1 (0.54) L3MBTL1GAACES2CES1AKR1B1
SCHEMBL3686805 0.71 NOS2 (0.44) L3MBTL1GRIN1GRIN2BNOS2CES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5279920-A Containing a hydrazide compound KONICA CORPORATION (JP) 1994-01-18 US disclosed
EP-0539925-A1 Silver halide photographic light sensitive material KONICA CORPORATION (JP) 1993-05-05 EP disclosed