Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GLS | O94925 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL934246 | 0.88 | ALDH1A1 (0.34) | USP2ALDH1A1TSHRHSD17B10LMNA | |
| SCHEMBL3691139 | 0.88 | ALDH1A1 (0.34) | USP2ALDH1A1TSHRHSD17B10LMNA | |
| SCHEMBL933488 | 0.86 | HCRTR1 (0.37) | — | |
| SCHEMBL933505 | 0.80 | CYP1A2 (0.36) | HSD17B10 | |
| SCHEMBL933478 | 0.80 | BACE1 (0.47) | — | |
| SCHEMBL970249 | 0.76 | BACE1 (0.36) | USP2ALDH1A1TSHRHSD17B10LMNA | |
| SCHEMBL2926274 | 0.73 | ALDH1A1 (0.35) | USP2ALDH1A1TSHRHSD17B10LMNA | |
| SCHEMBL2926279 | 0.73 | ALDH1A1 (0.35) | USP2ALDH1A1TSHRHSD17B10LMNA | |
| SCHEMBL932861 | 0.72 | CHRNA1 (0.32) | — | |
| SCHEMBL16056122 | 0.71 | HDAC1 (0.34) | ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2451793-A1 | BACE INHIBITORS | Eli Lilly and Company (US) | 2012-05-16 | — | — | EP | disclosed |
| WO-2011005738-A1 | BACE INHIBITORS | ELI LILLY AND COMPANY (US) | 2011-01-13 | — | — | WO | disclosed |