Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCI | P41743 | 1/20 | 0.54 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.50 |
| ▸ | CTSV | O60911 | 1/20 | 0.48 |
| ▸ | CTSL | P07711 | 1/20 | 0.48 |
| ▸ | CTSS | P25774 | 1/20 | 0.48 |
| ▸ | F10 | P00742 | 1/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.47 |
| ▸ | ABHD6 | Q9BV23 | 2/20 | 0.46 |
| ▸ | MGLL | Q99685 | 1/20 | 0.46 |
| ▸ | PLA2G10 | O15496 | 3/20 | 0.44 |
| ▸ | PLA2G2A | P14555 | 3/20 | 0.44 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.44 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.44 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.44 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.44 |
| ▸ | PLA2G12B | Q9BX93 | 1/20 | 0.44 |
| ▸ | PLA2G12A | Q9BZM1 | 1/20 | 0.44 |
| ▸ | PLA2G2F | Q9BZM2 | 1/20 | 0.44 |
| ▸ | PLA2G3 | Q9NZ20 | 1/20 | 0.44 |
| ▸ | PLA2G2E | Q9NZK7 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL934603 | 0.86 | PSMB5 (0.53) | PRMT6CTSVCTSLCTSSF10 | |
| SCHEMBL933898 | 0.83 | CYP17A1 (0.49) | F10PRSS1ROCK1ALDH1A1CYP3A4 | |
| SCHEMBL1286079 | 0.80 | CYP3A4 (0.54) | ALDH1A1CYP3A4 | |
| SCHEMBL951716 | 0.79 | CTSV (0.52) | CTSVCTSLCTSSROCK1ROCK2 | |
| SCHEMBL952137 | 0.79 | CTSV (0.52) | CTSVCTSLCTSSPLA2G10PLA2G2A | |
| SCHEMBL31369767 | 0.78 | GRIA2 (0.69) | PRKCIGRIA2 | |
| SCHEMBL31369588 | 0.78 | GRIA2 (0.69) | PRKCIGRIA2 | |
| SCHEMBL15881159 | 0.78 | CTSV (0.53) | CTSVCTSLCTSSPLA2G10PLA2G2A | |
| SCHEMBL28964214 | 0.76 | PRMT6 (0.56) | PRKCIPRMT6CTSVCTSLCTSS | |
| SCHEMBL28964216 | 0.76 | PRMT6 (0.56) | PRKCIPRMT6CTSVCTSLCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011006935-A2 | TETRAZOLE DERIVATIVES | MERCK SERONO S.A. (CH) | 2011-01-20 | — | — | WO | disclosed |