Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSV | O60911 | 1/20 | 0.52 |
| ▸ | CTSL | P07711 | 1/20 | 0.52 |
| ▸ | CTSB | P07858 | 1/20 | 0.52 |
| ▸ | CTSS | P25774 | 1/20 | 0.52 |
| ▸ | ROCK2 | O75116 | 16/20 | 0.47 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.47 |
| ▸ | ROCK1 | Q13464 | 7/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23815431 | 0.82 | CTSS (0.50) | CTSVCTSLCTSBCTSSROCK2 | |
| SCHEMBL934603 | 0.79 | PSMB5 (0.53) | CTSVCTSLCTSBCTSSLRRK2 | |
| SCHEMBL933472 | 0.79 | PRKCI (0.54) | CTSVCTSLCTSSROCK2LRRK2 | |
| SCHEMBL952137 | 0.77 | CTSV (0.52) | CTSVCTSLCTSBCTSS | |
| SCHEMBL951718 | 0.76 | ROCK2 (0.50) | CTSVCTSLCTSBCTSSROCK2 | |
| SCHEMBL13737919 | 0.75 | GRIN2D (0.56) | CTSVCTSLCTSBCTSSROCK2 | |
| SCHEMBL7998694 | 0.74 | IDO1 (0.59) | CTSVCTSLCTSBCTSSROCK2 | |
| SCHEMBL22501830 | 0.72 | ROCK2 (0.59) | CTSVCTSLCTSBCTSSROCK2 | |
| SCHEMBL3663278 | 0.72 | CCNT1 (0.52) | ROCK2ROCK1GSK3BDYRK1A | |
| SCHEMBL951717 | 0.72 | ROCK2 (0.56) | ROCK2ROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011006935-A2 | TETRAZOLE DERIVATIVES | MERCK SERONO S.A. (CH) | 2011-01-20 | — | — | WO | disclosed |