Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB5 | P28074 | 2/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.52 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.52 |
| ▸ | CTSV | O60911 | 1/20 | 0.50 |
| ▸ | CTSL | P07711 | 1/20 | 0.50 |
| ▸ | CTSB | P07858 | 1/20 | 0.50 |
| ▸ | CTSS | P25774 | 1/20 | 0.50 |
| ▸ | F2 | P00734 | 1/20 | 0.49 |
| ▸ | F10 | P00742 | 1/20 | 0.49 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.49 |
| ▸ | MKNK1 | Q9BUB5 | 9/20 | 0.49 |
| ▸ | MKNK2 | Q9HBH9 | 9/20 | 0.49 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.48 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.48 |
| ▸ | KMO | O15229 | 1/20 | 0.48 |
| ▸ | SYK | P43405 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.45 |
| ▸ | AXL | P30530 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL933472 | 0.86 | PRKCI (0.54) | PRMT6CTSVCTSLCTSSF10 | |
| SCHEMBL933922 | 0.86 | MKNK1 (0.55) | F2F10PRSS1MKNK1MKNK2 | |
| SCHEMBL933852 | 0.84 | TBXAS1 (0.60) | TBXAS1 | |
| SCHEMBL14732763 | 0.81 | EPHX2 (0.62) | PSMB5EPHX2PRMT6CTSVCTSL | |
| SCHEMBL31369586 | 0.80 | GRIA2 (0.66) | PSMB5EPHX2PRMT6CTSVCTSL | |
| SCHEMBL951716 | 0.79 | CTSV (0.52) | CTSVCTSLCTSBCTSSLRRK2 | |
| SCHEMBL21369072 | 0.79 | EPHX2 (0.55) | PSMB5EPHX2PRMT6CTSVCTSL | |
| SCHEMBL5176875 | 0.79 | EPHX2 (0.55) | PSMB5EPHX2PRMT6MKNK1MKNK2 | |
| SCHEMBL7675391 | 0.78 | KMO (0.54) | PSMB5EPHX2PRMT6CTSVCTSL | |
| SCHEMBL952137 | 0.76 | CTSV (0.52) | CTSVCTSLCTSBCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011006935-A2 | TETRAZOLE DERIVATIVES | MERCK SERONO S.A. (CH) | 2011-01-20 | — | — | WO | disclosed |