SCHEMBL933552

SCHEMBL933552

Cc1cn([C@H]2C[C](O)[C@@H](CO)O2)c(=O)[nH]c1=O

nearest known ligand 0.59

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.54
ALB P02768 2/20 0.54
BLM P54132 2/20 0.54
ALDH1A1 P00352 1/20 0.54
POLB P06746 1/20 0.54
ADRA1A P35348 1/20 0.54
TK1 P04183 6/20 0.54
TSHR P16473 2/20 0.52
PKM P14618 1/20 0.52
PMP22 Q01453 1/20 0.52
CYP2D6 P10635 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2158702 0.88 LMNA (0.55) LMNAALBBLMALDH1A1POLB
SCHEMBL14232397 0.88 LMNA (0.55) LMNAALBBLMALDH1A1POLB
SCHEMBL12595723 0.86 TK1 (0.56) LMNAALBBLMALDH1A1POLB
SCHEMBL2159268 0.84 TK1 (0.52) LMNAALBBLMALDH1A1POLB
SCHEMBL18837842 0.80 TK1 (0.66) LMNAALBBLMTK1TSHR
SCHEMBL25966495 0.79 TK1 (0.52) LMNAALBBLMALDH1A1POLB
SCHEMBL417308 0.79 LMNA (0.60) LMNAALBBLMALDH1A1POLB
SCHEMBL14596607 0.77 LMNA (0.58) LMNAALBBLMALDH1A1POLB
SCHEMBL13286394 0.77 LMNA (0.58) LMNAALBBLMALDH1A1POLB
SCHEMBL762579 0.77 LMNA (0.58) LMNAALBBLMALDH1A1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112533892-B Alkoxyphenyl derivative, nucleoside protector, nucleotide protector, method for producing oligonucleotide, and method for removing substituent 藤本化学制品株式会社 2023-09-08 CN disclosed
CN-112533892-A Alkoxyphenyl derivative, nucleoside protector and nucleotide protector, method for producing oligonucleotide, and method for removing substituent 藤本化学制品株式会社 2021-03-19 CN disclosed
WO-2020017085-A1 ALKOXYPHENYL DERIVATIVE, NUCLEOSIDE PROTECTOR, NUCLEOTIDE PROTECTOR, METHOD FOR PRODUCING OLIGONUCLEOTIDE, AND METHOD FOR REMOVING SUBSTITUENT 藤本化学製品株式会社 2020-01-23 WO disclosed
EP-2451461-A1 NOVEL NUCLEIC ACID PRODRUGS AND METHODS OF USE THEREOF Ontorii, Inc (US) 2012-05-16 EP disclosed
WO-2011005761-A1 NOVEL NUCLEIC ACID PRODRUGS AND METHODS USE THEREOF ONTORII, INC (US) 2011-01-13 WO disclosed
WO-1996016073-A2 CODON AMIDITES AND METHOD OF USING THEM TO PRODUCE OLIGONUCLEOTIDES AND MUTAGENESIS LIBRARIES TERRAPIN TECHNOLOGIES, INC. (US) 1996-05-30 WO disclosed