Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPG | P10696 | 8/20 | 0.59 |
| ▸ | ALPL | P05186 | 7/20 | 0.59 |
| ▸ | NSD2 | O96028 | 5/20 | 0.52 |
| ▸ | GAA | P10253 | 4/20 | 0.52 |
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | GFER | P55789 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | PLAA | Q9Y263 | 5/20 | 0.45 |
| ▸ | ALPI | P09923 | 3/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9256725 | 0.99 | ALPG (0.61) | ALPGALPLNSD2GAAPOLB | |
| SCHEMBL9356659 | 0.79 | ALPG (0.70) | ALPGALPLNSD2GAAPOLB | |
| SCHEMBL9248506 | 0.72 | ADRB2 (0.41) | GAAKMT2AALDH1A1MEN1KDM4E | |
| Hydrochloric Acid SCHEMBL9336175 | 0.71 | ADRB2 (0.43) | GAAPOLBKMT2AALDH1A1MEN1 | |
| SCHEMBL6403309 | 0.70 | ALPG (0.64) | ALPGALPLNSD2GAAPOLB | |
| SCHEMBL9257201 | 0.69 | BACE1 (0.44) | POLBALDH1A1GFERKDM4E | |
| Hydrochloric Acid SCHEMBL31419976 | 0.69 | ALPL (0.59) | ALPGALPLNSD2GAAPOLB | |
| Hydrochloric Acid SCHEMBL9253720 | 0.68 | ACHE (0.43) | POLBALDH1A1GFERKDM4E | |
| SCHEMBL9249214 | 0.68 | ALDH1A1 (0.43) | GAAKMT2AALDH1A1MEN1KDM4E | |
| SCHEMBL31419974 | 0.68 | NSD2 (0.69) | ALPLNSD2GAAPOLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0326379-B1 | Therapeutic agent for liver disease and piperazine derivatives | NIPPON CHEMIPHAR CO (JP) | 1994-06-01 | — | — | EP | disclosed |
| US-5070089-A | INHIBITION OF LIPID PEROXIDATION | NIPPON CHEMIPHAR CO., LTD. (JP) | 1991-12-03 | — | — | US | disclosed |
| EP-0326379-A2 | Therapeutic agent for liver disease and piperazine derivatives | NIPPON CHEMIPHAR CO., LTD. (JP) | 1989-08-02 | — | — | EP | disclosed |