Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4A | O75164 | 1/20 | 0.45 |
| ▸ | PHGDH | O43175 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | FAAH | O00519 | 1/20 | 0.30 |
| ▸ | JAK2 | O60674 | 1/20 | 0.30 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.30 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | FBP1 | P09467 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1758512 | 0.85 | — | — | |
| SCHEMBL10488729 | 0.83 | — | — | |
| SCHEMBL16508419 | 0.83 | KDM4A (0.35) | KDM4APHGDH | |
| SCHEMBL7079466 | 0.81 | MGLL (0.65) | KDM4APHGDHL3MBTL1KDM4EMEN1 | |
| SCHEMBL1057812 | 0.77 | — | — | |
| SCHEMBL12965179 | 0.77 | ALDH1A1 (0.40) | KDM4APHGDHL3MBTL1KDM4EMEN1 | |
| SCHEMBL6908941 | 0.74 | — | — | |
| SCHEMBL22471733 | 0.72 | — | — | |
| SCHEMBL20601185 | 0.72 | — | — | |
| Dimethylamine SCHEMBL20601195 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-5058812-A | — | — | None | — | — | JP | disclosed |
| US-10329318-B2 | Method for the synthesis of phosphorus atom modified nucleic acids | WAVE LIFE SCIENCES LTD. (SG) | 2019-06-25 | — | — | US | disclosed |
| US-10329318-B2 | Method for the synthesis of phosphorus atom modified nucleic acids | WAVE LIFE SCIENCES LTD. (SG) | 2019-06-25 | — | — | US | disclosed |
| US-10307434-B2 | Nucleic acid prodrugs and methods of use thereof | WAVE LIFE SCIENCES LTD. (SG) | 2019-06-04 | — | — | US | disclosed |
| US-20180111958-A1 | METHOD FOR THE SYNTHESIS OF PHOSPHORUS ATOM MODIFIED NUCLEIC ACIDS | WAVE LIFE SCIENCES JAPAN, INC. (JP) | 2018-04-26 | — | — | US | disclosed |
| US-20180111958-A1 | METHOD FOR THE SYNTHESIS OF PHOSPHORUS ATOM MODIFIED NUCLEIC ACIDS | WAVE LIFE SCIENCES JAPAN, INC. (JP) | 2018-04-26 | — | — | US | disclosed |
| US-20180111958-A1 | METHOD FOR THE SYNTHESIS OF PHOSPHORUS ATOM MODIFIED NUCLEIC ACIDS | WAVE LIFE SCIENCES JAPAN, INC. (JP) | 2018-04-26 | — | — | US | disclosed |
| US-9744183-B2 | Nucleic acid prodrugs and methods of use thereof | WAVE LIFE SCIENCES LTD. (SG) | 2017-08-29 | — | — | US | disclosed |
| US-9695211-B2 | Method for the synthesis of phosphorus atom modified nucleic acids | WAVE LIFE SCIENCES JAPAN, INC. (JP) | 2017-07-04 | — | — | US | disclosed |
| US-9695211-B2 | Method for the synthesis of phosphorus atom modified nucleic acids | WAVE LIFE SCIENCES JAPAN, INC. (JP) | 2017-07-04 | — | — | US | disclosed |
| US-20120316224-A1 | NOVEL NUCLEIC ACID PRODRUGS AND METHODS OF USE THEREOF | ONTORII, INC (US) | 2012-12-13 | — | — | US | disclosed |
| EP-2451461-A1 | NOVEL NUCLEIC ACID PRODRUGS AND METHODS OF USE THEREOF | Ontorii, Inc (US) | 2012-05-16 | — | — | EP | disclosed |
| US-20110294124-A1 | METHOD FOR THE SYNTHESIS OF PHOSPHORUS ATOM MODIFIED NUCLEIC ACIDS | WAVE LIFE SCIENCES LTD. (SG) | 2011-12-01 | — | — | US | disclosed |
| US-20110294124-A1 | METHOD FOR THE SYNTHESIS OF PHOSPHORUS ATOM MODIFIED NUCLEIC ACIDS | WAVE LIFE SCIENCES LTD. (SG) | 2011-12-01 | — | — | US | disclosed |
| US-20110294124-A1 | METHOD FOR THE SYNTHESIS OF PHOSPHORUS ATOM MODIFIED NUCLEIC ACIDS | WAVE LIFE SCIENCES LTD. (SG) | 2011-12-01 | — | — | US | disclosed |
| WO-2011005761-A1 | NOVEL NUCLEIC ACID PRODRUGS AND METHODS USE THEREOF | ONTORII, INC (US) | 2011-01-13 | — | — | WO | disclosed |
| EP-0633918-A1 | ULTRAVIOLET RADIATION CURABLE ACRYLATE PRESSURE-SENSITIVE ADHESIVE COMPOSITIONS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1995-01-18 | — | — | EP | disclosed |
| WO-1993020164-A1 | ULTRAVIOLET RADIATION CURABLE ACRYLATE PRESSURE-SENSITIVE ADHESIVE COMPOSITIONS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1993-10-14 | — | — | WO | disclosed |
| JP-H0558812-A | METHOD FOR CONTROLLING DISEASE DAMAGE OF RICE PLANT | HOKKO CHEM IND CO LTD | 1993-03-09 | — | — | JP | disclosed |
| JP-H00558812-A | — | — | 0001-01-01 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180111958-A1 | METHOD FOR THE SYNTHESIS OF PHOSPHORUS ATOM MODIFIED NUCLEIC ACIDS | PNP, ADAR, NUDT1 | KDM4A 3873/4885PHGDH 465/4885CA12 1775/4885 |
| US-20120316224-A1 | NOVEL NUCLEIC ACID PRODRUGS AND METHODS OF USE THEREOF | PNP, RNGTT, TYMP | KDM4A 2329/4885PHGDH 280/4885CA12 1205/4885 |
| US-10329318-B2 | Method for the synthesis of phosphorus atom modified nucleic acids | PNP, ADAR, NUDT1 | KDM4A 3873/4885PHGDH 465/4885CA12 1775/4885 |
| US-20110294124-A1 | METHOD FOR THE SYNTHESIS OF PHOSPHORUS ATOM MODIFIED NUCLEIC ACIDS | PNP, ADAR, NUDT1 | KDM4A 3873/4885PHGDH 465/4885CA12 1775/4885 |
| US-10307434-B2 | Nucleic acid prodrugs and methods of use thereof | PNP, RNGTT, NSUN2 | KDM4A 2616/4885PHGDH 281/4885CA12 1080/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.