Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 5/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | DAO | P14920 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | IAPP | P10997 | 1/20 | 0.35 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.35 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8797884 | 0.77 | HRH1 (0.51) | MPOSLC6A4TAAR1MGLLHSPA5 | |
| SCHEMBL4967651 | 0.75 | TAAR1 (0.65) | MPOSLC6A4TAAR1MGLLHTR1A | |
| SCHEMBL8665678 | 0.74 | CCR1 (0.41) | MAPTSMN1; SMN2KMT2ADAONPC1 | |
| SCHEMBL10438887 | 0.73 | TAAR1 (0.62) | MPOSLC6A4TAAR1MGLLHTR1A | |
| SCHEMBL18682734 | 0.73 | CCR1 (0.52) | MAPTKMT2ADAORAB9A | |
| SCHEMBL20099862 | 0.73 | PDE10A (0.42) | MAPTSMN1; SMN2KMT2ADAONPC1 | |
| SCHEMBL798358 | 0.73 | CYP2C19 (0.46) | TAAR1SMN1; SMN2RAB9A | |
| SCHEMBL933038 | 0.73 | NPSR1 (0.55) | MAPTTAAR1SMN1; SMN2KMT2A | |
| SCHEMBL12040589 | 0.72 | RAB9A (0.50) | SMN1; SMN2KMT2ANPC1RAB9A | |
| SCHEMBL9921222 | 0.72 | ALDH1A1 (0.44) | MAPTSMN1; SMN2KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2451781-A1 | PYRIDINE DERIVATIVES WITH UMAMI FLAVOUR | Givaudan SA (CH) | 2012-05-16 | — | — | EP | disclosed |
| WO-2011004016-A1 | PYRIDINE DERIVATIVES WITH UMAMI FLAVOUR | GIVAUDAN SA (CH) | 2011-01-13 | — | — | WO | disclosed |