Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 1/20 | 0.44 |
| ▸ | CTSK | P43235 | 1/20 | 0.44 |
| ▸ | CTSG | P08311 | 1/20 | 0.39 |
| ▸ | CMA1 | P23946 | 1/20 | 0.39 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TACR1 | P25103 | 1/20 | 0.37 |
| ▸ | PLAU | P00749 | 1/20 | 0.36 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.36 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.36 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9867660 | 0.90 | CTSS (0.49) | CTSSCTSKUSP30CTNNB1 | |
| SCHEMBL9867667 | 0.90 | CTSS (0.49) | CTSSCTSKUSP30CTNNB1 | |
| SCHEMBL9866632 | 0.90 | ITGB3 (0.42) | CTSSCTSKTACR1PLAU | |
| Iodide SCHEMBL9866617 | 0.89 | ITGB3 (0.41) | CTSSCTSKTACR1PLAU | |
| SCHEMBL9335977 | 0.88 | KMT2A (0.43) | CTSGCMA1MEN1NPC1RAB9A | |
| SCHEMBL9865704 | 0.84 | CTSK (0.44) | CTSSCTSKTACR1 | |
| SCHEMBL9337488 | 0.84 | ITGB3 (0.47) | CTSSCTSKPLAUCTNNB1 | |
| SCHEMBL9335862 | 0.82 | CTSS (0.45) | CTSSCTSKTACR1PSMB8PSMB5 | |
| SCHEMBL9337444 | 0.80 | CTSS (0.44) | CTSSCTSKPLAUCTNNB1PSMB8 | |
| Iodide SCHEMBL9866746 | 0.80 | CTSS (0.44) | CTSSCTSKPLAUCTNNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5008275-A | Fungicides | BAYER AKTIENGESELLSCHAFT (DE) | 1991-04-16 | — | — | US | claimed |
| EP-0372486-B1 | Benzoic-acid phenylacetic-acid derivatives, their preparation and their use as medicines | HOFFMANN LA ROCHE (CH) | 1994-06-01 | — | — | EP | disclosed |
| US-5039805-A | Novel benzoic and phenylacetic acid derivatives | HOFFMANN-LA ROCHE INC. (US) | 1991-08-13 | — | — | US | disclosed |
| EP-0372486-A2 | Benzoic-acid phenylacetic-acid derivatives, their preparation and their use as medicines | F. HOFFMANN-LA ROCHE AG (CH) | 1990-06-13 | — | — | EP | disclosed |