Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 2/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.42 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 11/20 | 0.40 |
| ▸ | PLAU | P00749 | 4/20 | 0.39 |
| ▸ | F2 | P00734 | 6/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 6/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.39 |
| ▸ | PLG | P00747 | 1/20 | 0.39 |
| ▸ | PLAT | P00750 | 1/20 | 0.39 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.39 |
| ▸ | TACR1 | P25103 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL9866617 | 0.99 | ITGB3 (0.41) | ITGB3ITGA2BCTSSCTSKF10 | |
| SCHEMBL9337488 | 0.94 | ITGB3 (0.47) | ITGB3ITGA2BCTSSCTSKPLAU | |
| SCHEMBL9337361 | 0.90 | CTSS (0.44) | CTSSCTSKPLAUTACR1 | |
| Iodide SCHEMBL9866746 | 0.90 | CTSS (0.44) | ITGB3ITGA2BCTSSCTSKF10 | |
| Iodide SCHEMBL9866737 | 0.90 | CTSS (0.44) | ITGB3ITGA2BCTSSCTSKF10 | |
| SCHEMBL9337552 | 0.88 | ITGB3 (0.49) | ITGB3ITGA2BF10PLAUF2 | |
| Iodide SCHEMBL9337538 | 0.88 | ITGB3 (0.48) | ITGB3ITGA2BF10PLAUF2 | |
| SCHEMBL9865704 | 0.85 | CTSK (0.44) | CTSSCTSKTACR1 | |
| SCHEMBL9335862 | 0.85 | CTSS (0.45) | CTSSCTSKTACR1 | |
| SCHEMBL9339303 | 0.85 | ITGB3 (0.48) | ITGB3ITGA2BCTSSCTSKF10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5039805-A | Novel benzoic and phenylacetic acid derivatives | HOFFMANN-LA ROCHE INC. (US) | 1991-08-13 | — | — | US | disclosed |