SCHEMBL9338342

SCHEMBL9338342

C#Cc1ccc2c(c1)C(=O)N(C)C2=O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.50
HSD17B10 Q99714 4/20 0.47
MEN1 O00255 2/20 0.47
MAPT P10636 2/20 0.47
KMT2A Q03164 2/20 0.47
L3MBTL1 Q9Y468 2/20 0.47
ALOX15 P16050 1/20 0.47
APP P05067 7/20 0.46
HPGD P15428 4/20 0.46
MAPK1 P28482 1/20 0.46
GABRA1 P14867 3/20 0.43
GABRA5 P31644 3/20 0.43
GABRA2 P47869 3/20 0.43
GABRB2 P47870 3/20 0.43
GABRA3 P34903 2/20 0.43
GABRG2 P18507 1/20 0.43
GABRB3 P28472 1/20 0.43
CASP3 P42574 2/20 0.42
KDM4E B2RXH2 3/20 0.41
POLB P06746 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18962220 0.85 HPGD (0.41) ALDH1A1HSD17B10MEN1MAPTKMT2A
SCHEMBL15326995 0.84 ALDH1A1 (0.53) ALDH1A1HSD17B10MEN1MAPTKMT2A
SCHEMBL12235636 0.80 POLB (0.53) ALDH1A1HSD17B10MEN1KMT2AKDM4E
SCHEMBL21028319 0.79 ALDH1A1 (0.49) ALDH1A1HSD17B10MEN1MAPTKMT2A
SCHEMBL23980507 0.78 APP (0.56) ALDH1A1HSD17B10MEN1MAPTKMT2A
SCHEMBL20457806 0.78 GABRA1 (0.34) ALDH1A1HSD17B10MEN1MAPTKMT2A
SCHEMBL13444931 0.78 ALDH1A1 (0.59) ALDH1A1HSD17B10MEN1KMT2AHPGD
SCHEMBL83864 0.77 GRM5 (0.60) ALDH1A1HSD17B10MEN1MAPTKMT2A
SCHEMBL18962208 0.76 APP (0.43) ALDH1A1HSD17B10MEN1MAPTKMT2A
SCHEMBL9339024 0.75 GABRA1 (0.48) ALDH1A1HSD17B10MEN1MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0411304-B1 Acetylene bis-phthalic compounds and polyimides made therefrom GEN ELECTRIC (US) 1994-06-15 EP claimed
EP-0411304-A1 Acetylene bis-phthalic compounds and polyimides made therefrom GENERAL ELECTRIC COMPANY (US) 1991-02-06 EP claimed
US-20240231231-A1 METHOD FOR FORMING RESIST UNDERLAYER FILM, METHOD FOR PRODUCING SEMICONDUCTOR SUBSTRATE, COMPOSITION, AND RESIST UNDERLAYER FILM JSR CORPORATION (JP) 2024-07-11 US disclosed
US-11746184-B2 Polyimide-polyarylene polymers ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) 2023-09-05 US disclosed
US-20230260787-A1 COMPOSITION FOR FORMING PROTECTIVE FILM AGAINST ALKALINE AQUEOUS HYDROGEN PEROXIDE, SUBSTRATE FOR PRODUCING SEMICONDUCTOR APPARATUS, METHOD FOR FORMING PROTECTIVE FILM, AND METHOD FOR FORMING PATTERN SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-08-17 US disclosed
US-11676814-B2 Material for forming organic film, substrate for manufacturing semiconductor apparatus, method for forming organic film, and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-06-13 US disclosed
US-11186757-B2 Resin composition, resin layer, permanent adhesive, adhesive for temporary bonding, laminated film, processed wafer, and method for manufacturing electronic component or semiconductor device TORAY INDUSTRIES, INC. (JP) 2021-11-30 US disclosed
US-20210181637-A1 MATERIAL FOR FORMING ORGANIC FILM, METHOD FOR FORMING ORGANIC FILM, PATTERNING PROCESS, AND COMPOUND SHIN-ETSU CHEMICAL CO., LTD. (JP) 2021-06-17 US disclosed
US-20210139700-A1 RESIN COMPOSITION, RESIN LAYER, PERMANENT ADHESIVE, ADHESIVE FOR TEMPORARY BONDING, LAMINATED FILM, PROCESSED WAFER, AND METHOD FOR MANUFACTURING ELECTRONIC COMPONENT OR SEMICONDUCTOR DEVICE TORAY INDUSTRIES, INC. (JP) 2021-05-13 US disclosed
US-20190163061-A1 POLYIMIDE PRECURSOR AND LITHOGRAPHY PATTERN FORMED BY THE SAME TAIFLEX SCIENTIFIC CO., LTD. (TW) 2019-05-30 US disclosed
US-10177022-B2 Adhesive for temporary bonding, adhesive layer, wafer work piece and method for manufacturing semiconductor device using same, rework solvent, polyimide copolymer, polyimide mixed resin, and resin composition TORAY INDUSTRIES, INC. (JP) 2019-01-08 US disclosed
US-20170168391-A1 PHOTOSENSITIVE RESIN COMPOSITION, METHOD FOR PRODUCING CURED FILM, CURED FILM, LIQUID CRYSTAL DISPLAY DEVICE, ORGANIC ELECTROLUMINESCENT DISPLAY DEVICE, AND TOUCH PANEL FUJIFILM CORPORATION (JP) 2017-06-15 US disclosed
EP-2899179-A1 Combination of cross-linkers including carbon-carbon triple bonds Nexam Chemical AB (SE) 2015-07-29 EP disclosed
US-8106142-B2 Polyacetylinic oligomers THE BOEING COMPANY (US) 2012-01-31 US disclosed
US-8063168-B2 Oligomers with di-phenylethynyl endcaps THE BOEING COMPANY (US) 2011-11-22 US disclosed
US-20100204485-A1 POLYACETYLINIC OLIGOMERS THE BOEING COMPANY 2010-08-12 US disclosed
US-20100204412-A1 OLIGOMERS WITH DI-PHENYLETHYNYL ENDCAPS THE BOEING COMPANY 2010-08-12 US disclosed
EP-0411304-B1 Acetylene bis-phthalic compounds and polyimides made therefrom GEN ELECTRIC (US) 1994-06-15 EP disclosed
EP-0411304-A1 Acetylene bis-phthalic compounds and polyimides made therefrom GENERAL ELECTRIC COMPANY (US) 1991-02-06 EP disclosed
US-4973707-A Acetylene bis-phthalic compounds and polyimides made therefrom GENERAL ELECTRIC COMPANY (US) 1990-11-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11746184-B2 Polyimide-polyarylene polymers PAICS, PIN1, PARN ALDH1A1 2532/4885HSD17B10 1210/4885MEN1 3007/4885
US-20210181637-A1 MATERIAL FOR FORMING ORGANIC FILM, METHOD FOR FORMING ORGANIC FILM, PATTERNING PROCESS, AND COMPOUND CDH1, VCL, OR10J3 ALDH1A1 1348/4885HSD17B10 2979/4885MEN1 770/4885
US-20100204485-A1 POLYACETYLINIC OLIGOMERS AADAC, ACMSD, ECPAS ALDH1A1 495/4885HSD17B10 1156/4885MEN1 4503/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.