Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | TK1 | P04183 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20636773 | 0.90 | LMNA (0.38) | LMNASMN1; SMN2HSP90AA1ALOX12ADRA1A | |
| SCHEMBL1727535 | 0.88 | RNASE1 (0.40) | TK1 | |
| SCHEMBL4856132 | 0.87 | HSP90AA1 (0.38) | LMNASMN1; SMN2HSP90AA1TK1TSHR | |
| SCHEMBL7640415 | 0.82 | RNASE1 (0.38) | TK1 | |
| SCHEMBL8370048 | 0.82 | RNASE1 (0.38) | TK1 | |
| SCHEMBL7863893 | 0.80 | RNASE1 (0.37) | TK1 | |
| SCHEMBL1706305 | 0.79 | RNASE1 (0.38) | TK1 | |
| SCHEMBL9755145 | 0.79 | RNASE1 (0.38) | TK1 | |
| SCHEMBL9339166 | 0.79 | LMNA (0.44) | LMNASMN1; SMN2ALOX12ADRA1ATK1 | |
| SCHEMBL3612838 | 0.79 | TK1 (0.38) | LMNASMN1; SMN2ALOX12ADRA1ATK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110257493-A | DNA encoding library with the unreadable Encoding oligonucleotides connection of polymerase | X-化学有限公司 | 2019-09-20 | — | — | CN | disclosed |
| EP-0301873-B1 | 2'-deoxy-5-fluorouridine derivatives | TAIHO PHARMACEUTICAL CO LTD (JP) | 1994-06-08 | — | — | EP | disclosed |
| EP-0301873-A2 | 2'-deoxy-5-fluorouridine derivatives | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 1989-02-01 | — | — | EP | disclosed |